608512-97-6
608512-97-6 structure
- Name: Imidazolo-oxindole PKR inhibitor C16
- Chemical Name: Imidazolo-oxindole PKR inhibitor C16
- CAS Number: 608512-97-6
- Molecular Formula: C13H8N4OS
- Molecular Weight: 268.294
- Catalog: Research Areas Neurological Disease
- Create Date: 2016-06-22 02:31:31
- Modify Date: 2024-01-13 14:39:57
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PKR-IN-C16 is a specific protein kinase (PKR) inhibitor. PKR-IN-C16 is able to inhibit the autophosphorylation of PKR and unlock the translation blockade induced by PKR in primary neuronal cultures[1].
| Name | Imidazolo-oxindole PKR inhibitor C16 |
|---|---|
| Synonyms |
(8Z)-8-(1H-imidazol-4-ylmethylidene)-6,8-dihydro-7H-[1,3]thiazolo[5,4-e]indol-7-one
(Z)-8-((1H-Imidazol-4-yl)methylene)-6H-thiazolo[5,4-e]indol-7(8H)-one 8-(1H-Imidazol-4-ylmethylene)-6,8-dihydro-thiazolo[5,4-e]indol-7-one (8Z)-8-(1H-Imidazol-5-ylmethylene)-6,8-dihydro-7H-[1,3]thiazolo[5,4-e]indol-7-one C16 (PKR inhibitor) 7H-Thiazolo[5,4-e]indol-7-one, 6,8-dihydro-8-(1H-imidazol-5-ylmethylene)-, (8Z)- |
| Description | PKR-IN-C16 is a specific protein kinase (PKR) inhibitor. PKR-IN-C16 is able to inhibit the autophosphorylation of PKR and unlock the translation blockade induced by PKR in primary neuronal cultures[1]. |
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| Related Catalog | |
| References |
| Density | 1.6±0.1 g/cm3 |
|---|---|
| Boiling Point | 674.6±55.0 °C at 760 mmHg |
| Molecular Formula | C13H8N4OS |
| Molecular Weight | 268.294 |
| Flash Point | 361.8±31.5 °C |
| Exact Mass | 268.041870 |
| PSA | 98.91000 |
| LogP | 0.80 |
| Vapour Pressure | 0.0±2.1 mmHg at 25°C |
| Index of Refraction | 1.851 |
| RIDADR | NONH for all modes of transport |
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