84697-22-3

84697-22-3 structure

Name: (+/-)-CIS-3-METHYL-2-PIPERIDINECARBOXYLICACID
Chemical Name: (+/-)-ethyl-cis-[4-[[2-(2,4-dichlorophenyl)-2-(1h-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]-methylthio]phenyl]-carbamate hydrochloride
CAS Number: 84697-22-3
Molecular Formula: C₂₃H₂₃Cl₂N₃O₄S
Molecular Weight: 508.42
Create Date: 2018-04-05 08:00:00
Modify Date: 2024-09-16 09:54:59
Tubulozole is an orally active synthetic microtubule inhibitor. Tubulozole can be used for the research of tumor[1].

Name	(+/-)-ethyl-cis-[4-[[2-(2,4-dichlorophenyl)-2-(1h-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]-methylthio]phenyl]-carbamate hydrochloride
Synonyms	tubulozole-C hydrochloride cis-tubulozole CIS-TUBULOZOLE HYDROCHLORIDE TUBULOZOLE-C TubulozolecHCl tubulazole TUBULOZOLE

Description	Tubulozole is an orally active synthetic microtubule inhibitor. Tubulozole can be used for the research of tumor[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Microtubule/Tubulin Signaling Pathways >> Cytoskeleton >> Microtubule/Tubulin
In Vivo	Tubulozole (oral; 160 mg/kg) 在体内具有抗微管和抗肿瘤作用[1]。 Animal Model: Male CDFi (DBA/Px C3H) hybrids (18-22 g)[1]. Dosage: 160 mg/kg Administration: Oral gavage Result: Had anti-microtubular and anti-tumor effect.
References	[1]. Distelmans W, et al. Influence of the synthetic microtubule inhibitor erbulozole (P.I.N.N.) (R 55 104), a new tubulozole congener, and gamma irradiation on murine tumors in vivo. Eur J Cancer Clin Oncol. 1989;25(10):1499-1504.

CHEMICAL NAME :: Carbamic acid, (4-(((2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethy l)-1,3-dioxolan-4-yl) methyl)thio)phenyl)-, ethyl ester, cis-(+-)-

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 244,95,1990