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Product Name: LONAZOLAC CALCIUM SALT
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75821-71-5

75821-71-5 structure

75821-71-5 structure

Name: LONAZOLAC CALCIUM SALT
Chemical Name: lonazolac calcium
CAS Number: 75821-71-5
Molecular Formula: C₃₄H₂₄CaCl₂N₄O₄
Molecular Weight: 663.56300
Catalog: Research Areas Inflammation/Immunology
Create Date: 2018-05-28 08:00:00
Modify Date: 2024-01-15 02:54:52
Lonazolac (hemicalcium) is the calcium salt form of Lonazolac. Lonazolac is a nonsteroidal antirheumatic agent with anti-inflammatory properties[1].

Name	lonazolac calcium
Synonyms	LONAZOLAC CALCIUM SALT Arthro akut Bis[1-phenyl-3-(4-chlorophenyl)-1H-pyrazole-4-acetic acid]calcium salt Argun l Irritren calcium bis[3-(4-chlorophenyl)-1-phenyl-1H-pyrazole-4-acetate] Lonazolac calcium 1H-Pyrazole-4-acetic acid,3-(4-chlorophenyl)-1-phenyl-,calcium salt (2:1) Bis[3-(4-chlorophenyl)-1-phenyl-1H-pyrazole-4-acetic acid]calcium salt

Description	Lonazolac (hemicalcium) is the calcium salt form of Lonazolac. Lonazolac is a nonsteroidal antirheumatic agent with anti-inflammatory properties[1].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology
References	[1]. Trnavský K, et al. [Lonazolac - a new non-steroidal antirheumatic agent. Report of a double-blind crossover clinical study]. Fysiatr Revmatol Vestn. 1983;61(3):147-152.

Boiling Point	525.1ºC at 760 mmHg
Molecular Formula	C₃₄H₂₄CaCl₂N₄O₄
Molecular Weight	663.56300
Flash Point	271.4ºC
Exact Mass	662.08000
PSA	115.90000
LogP	4.97020

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UQ4915000

CAS REGISTRY NUMBER :: 75821-71-5

LAST UPDATED :: 199409

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C34-H24-Cl2-N4-O4.Ca

MOLECULAR WEIGHT :: 663.60

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 845 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 31,655,1981

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 670 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 31,655,1981

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 650 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: MDACAP Medicamentos de Actualidad. (J.R. Prous, S.A., Apartado de Correos 540, 08080 Barcelona, Spain) V.1- 1965- Volume(issue)/page/year: 18,180,1982

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: 790 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: MDACAP Medicamentos de Actualidad. (J.R. Prous, S.A., Apartado de Correos 540, 08080 Barcelona, Spain) V.1- 1965- Volume(issue)/page/year: 18,180,1982