163217-74-1

163217-74-1 structure

Name: 2-Hydroxy atorvastatin lactone
Chemical Name: 2-Hydroxy Atorvastatin Lactone
CAS Number: 163217-74-1
Molecular Formula: C₃₃H₃₃FN₂O₅
Molecular Weight: 556.62400
Catalog: Research Areas Others
Create Date: 2018-08-13 09:51:27
Modify Date: 2024-01-04 08:29:23
2-Hydroxy atorvastatin lactone is a metabolite of Atorvastatin. Atorvastatin is an orally active HMG-CoA reductase inhibitor, has the ability to effectively decrease blood lipids[1][2].

Name	2-Hydroxy Atorvastatin Lactone
Synonyms	5-(4-fluorophenyl)-1-[2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl]-N-(2-hydroxyphenyl)-4-phenyl-2-propan-2-ylpyrrole-3-carboxamide

Description	2-Hydroxy atorvastatin lactone is a metabolite of Atorvastatin. Atorvastatin is an orally active HMG-CoA reductase inhibitor, has the ability to effectively decrease blood lipids[1][2].
Related Catalog	Research Areas >> Others
References	[1]. Guo CX, et al. Effects of Ginkgo biloba extracts on pharmacokinetics and efficacy of atorvastatin based on plasma indices. Xenobiotica. 2012;42(8):784‐790. [2]. Turner NA, et al. Comparison of the efficacies of five different statins on inhibition of human saphenous vein smooth muscle cell proliferation and invasion. J Cardiovasc Pharmacol. 2007 Oct;50(4):458-61.