2-Hydroxy atorvastatin lactone

Modify Date: 2025-08-26 21:03:19

2-Hydroxy atorvastatin lactone Structure
2-Hydroxy atorvastatin lactone structure
 Common Name 2-Hydroxy atorvastatin lactone
CAS Number 163217-74-1 Molecular Weight 556.62400
Density N/A Boiling Point N/A
Molecular Formula C33H33FN2O5 Melting Point 110-112ºC
MSDS N/A Flash Point N/A

 Use of 2-Hydroxy atorvastatin lactone


2-Hydroxy atorvastatin lactone is a metabolite of Atorvastatin. Atorvastatin is an orally active HMG-CoA reductase inhibitor, has the ability to effectively decrease blood lipids[1][2].

 Names

Name 2-Hydroxy Atorvastatin Lactone
Synonym More Synonyms

 2-Hydroxy atorvastatin lactone Biological Activity

Description 2-Hydroxy atorvastatin lactone is a metabolite of Atorvastatin. Atorvastatin is an orally active HMG-CoA reductase inhibitor, has the ability to effectively decrease blood lipids[1][2].
Related Catalog
References

[1]. Guo CX, et al. Effects of Ginkgo biloba extracts on pharmacokinetics and efficacy of atorvastatin based on plasma indices. Xenobiotica. 2012;42(8):784‐790.

[2]. Turner NA, et al. Comparison of the efficacies of five different statins on inhibition of human saphenous vein smooth muscle cell proliferation and invasion. J Cardiovasc Pharmacol. 2007 Oct;50(4):458-61.

 Chemical & Physical Properties

Melting Point 110-112ºC
Molecular Formula C33H33FN2O5
Molecular Weight 556.62400
Exact Mass 556.23700
PSA 100.79000
LogP 6.57210

 Synonyms

5-(4-fluorophenyl)-1-[2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl]-N-(2-hydroxyphenyl)-4-phenyl-2-propan-2-ylpyrrole-3-carboxamide
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