556813-39-9
556813-39-9 structure
- Name: CHIR 98014
- Chemical Name: 6-N-[2-[[4-(2,4-dichlorophenyl)-5-(1H-imidazol-2-yl)pyrimidin-2-yl]amino]ethyl]-3-nitropyridine-2,6-diamine
- CAS Number: 556813-39-9
- Molecular Formula: C20H17Cl2N9O2
- Molecular Weight: 486.314
- Catalog: Signaling Pathways PI3K/Akt/mTOR GSK-3
- Create Date: 2017-05-08 12:45:52
- Modify Date: 2025-08-25 11:19:52
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CHIR 98024 (Compound L) is a glycogen synthase kinase 3 (GSK3) inhibitor with an EC50 of 0.2566 μM[1].
| Name | 6-N-[2-[[4-(2,4-dichlorophenyl)-5-(1H-imidazol-2-yl)pyrimidin-2-yl]amino]ethyl]-3-nitropyridine-2,6-diamine |
|---|---|
| Synonyms |
2,6-Pyridinediamine, N-[2-[[4-(2,4-dichlorophenyl)-5-(1H-imidazol-2-yl)-2-pyrimidinyl]amino]ethyl]-3-nitro-
N-(2-{[4-(2,4-Dichlorophenyl)-5-(1H-imidazol-2-yl)-2-pyrimidinyl]amino}ethyl)-3-nitro-2,6-pyridinediamine CHIR-98014 |
| Description | CHIR 98024 (Compound L) is a glycogen synthase kinase 3 (GSK3) inhibitor with an EC50 of 0.2566 μM[1]. |
|---|---|
| Related Catalog | |
| Target |
GSK-3:0.2566 μM (EC50) |
| References |
[1]. Stephen D. Harrison, et al. Methods and compositions for the treatment of ischemia. WO2003074072A1. |
| Density | 1.6±0.1 g/cm3 |
|---|---|
| Boiling Point | 839.0±75.0 °C at 760 mmHg |
| Molecular Formula | C20H17Cl2N9O2 |
| Molecular Weight | 486.314 |
| Flash Point | 461.2±37.1 °C |
| Exact Mass | 485.088226 |
| PSA | 163.25000 |
| LogP | 3.76 |
| Vapour Pressure | 0.0±3.1 mmHg at 25°C |
| Index of Refraction | 1.753 |