206260-33-5

206260-33-5 structure

Name: Irampanel
Chemical Name: N,N-dimethyl-2-[2-(3-phenyl-1,2,4-oxadiazol-5-yl)phenoxy]ethanamine
CAS Number: 206260-33-5
Molecular Formula: C₁₈H₁₉N₃O₂
Molecular Weight: 309.36200
Catalog: Signaling Pathways Membrane Transporter/Ion Channel iGluR
Create Date: 2017-07-21 04:25:58
Modify Date: 2024-01-05 09:46:08
Irampanel (BIIR 561) is an AMPA receptor and voltage-dependent sodium channel blocker. Irampanel inhibits kainate-induced currents in rat cortical neurons[1].

Name	N,N-dimethyl-2-[2-(3-phenyl-1,2,4-oxadiazol-5-yl)phenoxy]ethanamine
Synonyms	Dimethyl-(2-(2-(3-phenyl-(1,2,4)oxadiazol-5-yl)phenoxy)ethyl)amine hydrochloride UNII-R2GZD7LMYX Irampanel [INN] Irampanel BIIR-561CL

Description	Irampanel (BIIR 561) is an AMPA receptor and voltage-dependent sodium channel blocker. Irampanel inhibits kainate-induced currents in rat cortical neurons[1].
Related Catalog	Signaling Pathways >> Neuronal Signaling >> iGluR Signaling Pathways >> Membrane Transporter/Ion Channel >> Sodium Channel Research Areas >> Neurological Disease Signaling Pathways >> Membrane Transporter/Ion Channel >> iGluR
Target	AMPA receptor
References	[1]. Weiser T, et al. Characterization of the anticonvulsant and neuroprotectant BIIR 561 CL in vitro: effects on native and recombinant alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors. Naunyn Schmiedebergs Arch Pharmacol. 2000 Nov;362(4-5):419-26.