22235-81-0

22235-81-0 structure

Name: N-Isopropylnoratropine (NINA)
Chemical Name: N-Isopropyl Noratropine
CAS Number: 22235-81-0
Molecular Formula: C₁₉H₂₇NO₃
Molecular Weight: 317.42300
Create Date: 2016-12-01 21:14:04
Modify Date: 2026-07-16 08:00:16
N-Isopropylnoratropine is used in the synthesis of ipratropium, a bronchodilator compound with nonselective muscarinic antagonist activity.

Name	N-Isopropyl Noratropine
Synonyms	Benzeneacetic acid, α-(hydroxymethyl)-, (3-endo)-8-(1-methylethyl)-8-azabicyclo[3.2.1]oct-3-yl ester (1R,3r,5S)-8-Isopropyl-8-azabicyclo[3.2.1]octan-3-yl 3-hydroxy-2-phenylpropanoate (Ipratropium Impurity) (1R,3r,5S)-8-isopropyl-8-azabicyclo[3.2.1]octan-3-yl 3-hydroxy-2-phenylpropanoate endo-(1)-8-Aza-8-isopropylbicyclo(3.2.1)oct-3-yl (hydroxymethyl)phenylacetate Ipratropium Bromide Impurity E Ipratropium Impurity E NIsopropylnoratropine,N Isopropylnoratropine N-Isopropyl Noratropine (Ipratropium Bromide Impurity E) N-Isopropylnoratropine YB-M2 Ipratropium Bromide Impurity 13(Ipratropium Impurity E) Ipratropium Bromide Impurity 13（Ipratropium Bromide Impurity E） endo-(±)-8-aza-8-isopropylbicyclo[3.2.1]oct-3-yl (hydroxymethyl)phenylacetate (8-propan-2-yl-8-azabicyclo[3.2.1]octan-3-yl) 3-hydroxy-2-phenylpropanoate rac-(R*)-α-(Hydroxymethyl)benzeneacetic acid (1R,5S)-8-isopropyl-8-azabicyclo[3.2.1]octane-3α-yl ester Ipratropium Bromide Impurity E (N-Isopropyl Noratropine) N-Isopropylnoratropine, 10 mM in DMSO N-DesMethyl IpratropiuM α-(HydroxyMethyl)benzeneacetic Acid (3-Endo)-8-(1-Methylethyl)-8-azabicyclo[3.2.1]- oct-3-yl Ester α-(HydroxyMethyl)benzeneacetic Acid endo-8-(1-Methylethyl)-8- azabicyclo[3.2.1]oct-3-yl Ester Ipratropium Bromide Impurity 13

HS Code	2933990090

67-64-1

16839-98-8

~63%

22235-81-0

Literature: Issa, Fatiah; Kassiou, Michael; Chan, Hak-Kim; McLeod, Malcolm D. Australian Journal of Chemistry, 2006 , vol. 59, # 1 p. 53 - 58

51-55-8

22235-81-0

Literature: Issa, Fatiah; Kassiou, Michael; Chan, Hak-Kim; McLeod, Malcolm D. Australian Journal of Chemistry, 2006 , vol. 59, # 1 p. 53 - 58

14510-37-3

22235-81-0

Literature: Tsyskovskaia, Irina; Kandil, Mustapha; Beaumier, Yves Synthetic Communications, 2007 , vol. 37, # 3 p. 439 - 446

3423-25-4

22235-81-0

Literature: Tsyskovskaia, Irina; Kandil, Mustapha; Beaumier, Yves Synthetic Communications, 2007 , vol. 37, # 3 p. 439 - 446

HS Code	2933990090
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%