141205-32-5

141205-32-5 structure

Name: Microcolin B
Chemical Name: [(2R,3S)-4-[[(2S)-2-[[(2R,4R)-2,4-dimethyloctanoyl]-methylamino]-4-methylpentanoyl]amino]-3-[methyl-[(2S)-3-methyl-1-[(2S)-2-[(2S)-2-methyl-5-oxo-2H-pyrrole-1-carbonyl]pyrrolidin-1-yl]-1-oxobutan-2-yl]amino]-4-oxobutan-2-yl] acetate
CAS Number: 141205-32-5
Molecular Formula: C₃₉H₆₅N₅O₈
Molecular Weight: 731.962
Catalog: Research Areas Inflammation/Immunology
Create Date: 2016-03-31 21:16:16
Modify Date: 2025-08-27 18:36:46
Microcolin B is an extremely potent unusual acylpeptide, proline-containing potent immunosuppressant. Microcolin B is isolated from blue-green alga Lyngbya majuscule[1].

Name	[(2R,3S)-4-[[(2S)-2-[[(2R,4R)-2,4-dimethyloctanoyl]-methylamino]-4-methylpentanoyl]amino]-3-[methyl-[(2S)-3-methyl-1-[(2S)-2-[(2S)-2-methyl-5-oxo-2H-pyrrole-1-carbonyl]pyrrolidin-1-yl]-1-oxobutan-2-yl]amino]-4-oxobutan-2-yl] acetate
Synonyms	(2R,3S)-4-({N-[(2R,4R)-2,4-Dimethyloctanoyl]-N-methyl-L-leucyl}amino)-3-(methyl{(2S)-3-methyl-1-[(2S)-2-{[(2S)-2-methyl-5-oxo-2,5-dihydro-1H-pyrrol-1-yl]carbonyl}-1-pyrrolidinyl]-1-oxo-2-butanyl}amino)-4-oxo-2-butanyl acetate Threoninamide,N-(2,4-dimethyl-1-oxooctyl)-N-methylleucyl-N-(1-((2-((2,5-dihydro-2-methyl-5-oxo-1H-pyrrol-1-yl)carbonyl)-1-pyrrolidinyl)carbonyl)-2-methylpropyl)-N-methyl-,acetate (ester) Octanamide, N-[(1S)-1-[[[(2S,3R)-3-(acetyloxy)-2-[[(1S)-1-[[(2S)-2-[[(2S)-2,5-dihydro-2-methyl-5-oxo-1H-pyrrol-1-yl]carbonyl]-1-pyrrolidinyl]carbonyl]-2-methylpropyl]methylamino]-1-oxobutyl]amino]carbonyl]-3-methylbutyl]-N,2,4-trimethyl-, (2R,4R)-

Description	Microcolin B is an extremely potent unusual acylpeptide, proline-containing potent immunosuppressant. Microcolin B is isolated from blue-green alga Lyngbya majuscule[1].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology
References	[1]. • Merritt B. Andrus, et al. Synthesis of Microcolin B, a Potent New Immunosuppressant Using an Efficient Mixed Imide Formation Reaction. J. Org. Chem. 1997, 62, 16, 5542–5549.