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24358-84-7

24358-84-7 structure
24358-84-7 structure
  • Name: Dexivacaine
  • Chemical Name: (2S)-N-(2,6-dimethylphenyl)-1-methylpiperidine-2-carboxamide
  • CAS Number: 24358-84-7
  • Molecular Formula: C15H22N2O
  • Molecular Weight: 246.35
  • Catalog: Research Areas Cardiovascular Disease
  • Create Date: 2018-03-17 08:00:00
  • Modify Date: 2024-01-11 17:15:34
  • (+)-Mepivacaine is a racemic isomer of Mepivacaine (HY-B0517), which has analgesic and vasoconstrictive activity. Mepivacaine is an amide type agent that temporarily causes local loss of consciousness. Mepivacaine binds to specific voltage-gated sodium channels on neuronal cell membranes, inhibiting sodium influx and membrane depolarization[1].

Name (2S)-N-(2,6-dimethylphenyl)-1-methylpiperidine-2-carboxamide
Synonyms Dexivacainum [INN-Latin]
(+)-Mepivacaine
Dexivacain
DEXIVACAINE
Dexivacaine [USAN:INN]
2',6'-Pipecoloxylidide,1-methyl-,L-(+)
(+)-1-Methyl-2',6'-pipecoloxylidide
(S)-Mepivacaine
Dexivacaina [INN-Spanish]
L(+)-Mepivacaine
Description (+)-Mepivacaine is a racemic isomer of Mepivacaine (HY-B0517), which has analgesic and vasoconstrictive activity. Mepivacaine is an amide type agent that temporarily causes local loss of consciousness. Mepivacaine binds to specific voltage-gated sodium channels on neuronal cell membranes, inhibiting sodium influx and membrane depolarization[1].
Related Catalog
References

[1]. Fairley J W, et al. An intradermal study of the local anaesthetic and vascular effects of the isomers of mepivacaine[J]. British Journal of Anaesthesia, 1981, 53(11): 1211-1216.

Density 1.077g/cm3
Boiling Point 383.1ºC at 760mmHg
Molecular Formula C15H22N2O
Molecular Weight 246.35
Flash Point 185.5ºC
Exact Mass 246.17300
PSA 35.83000
LogP 3.31360
Vapour Pressure 4.52E-06mmHg at 25°C
Index of Refraction 1.567