Dexivacaine

Modify Date: 2024-01-11 17:15:34

Dexivacaine Structure
Dexivacaine structure
Common Name Dexivacaine
CAS Number 24358-84-7 Molecular Weight 246.35
Density 1.077g/cm3 Boiling Point 383.1ºC at 760mmHg
Molecular Formula C15H22N2O Melting Point N/A
MSDS N/A Flash Point 185.5ºC

 Use of Dexivacaine


(+)-Mepivacaine is a racemic isomer of Mepivacaine (HY-B0517), which has analgesic and vasoconstrictive activity. Mepivacaine is an amide type agent that temporarily causes local loss of consciousness. Mepivacaine binds to specific voltage-gated sodium channels on neuronal cell membranes, inhibiting sodium influx and membrane depolarization[1].

 Names

Name (2S)-N-(2,6-dimethylphenyl)-1-methylpiperidine-2-carboxamide
Synonym More Synonyms

 Dexivacaine Biological Activity

Description (+)-Mepivacaine is a racemic isomer of Mepivacaine (HY-B0517), which has analgesic and vasoconstrictive activity. Mepivacaine is an amide type agent that temporarily causes local loss of consciousness. Mepivacaine binds to specific voltage-gated sodium channels on neuronal cell membranes, inhibiting sodium influx and membrane depolarization[1].
Related Catalog
References

[1]. Fairley J W, et al. An intradermal study of the local anaesthetic and vascular effects of the isomers of mepivacaine[J]. British Journal of Anaesthesia, 1981, 53(11): 1211-1216.

 Chemical & Physical Properties

Density 1.077g/cm3
Boiling Point 383.1ºC at 760mmHg
Molecular Formula C15H22N2O
Molecular Weight 246.35
Flash Point 185.5ºC
Exact Mass 246.17300
PSA 35.83000
LogP 3.31360
Vapour Pressure 4.52E-06mmHg at 25°C
Index of Refraction 1.567

 Synonyms

Dexivacainum [INN-Latin]
(+)-Mepivacaine
Dexivacain
DEXIVACAINE
Dexivacaine [USAN:INN]
2',6'-Pipecoloxylidide,1-methyl-,L-(+)
(+)-1-Methyl-2',6'-pipecoloxylidide
(S)-Mepivacaine
Dexivacaina [INN-Spanish]
L(+)-Mepivacaine