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133803-81-3

133803-81-3 structure
133803-81-3 structure
  • Name: Hydroxy-PEG2-(CH2)2-Boc
  • Chemical Name: tert-butyl 3-[2-(2-hydroxyethoxy)ethoxy]propanoate
  • CAS Number: 133803-81-3
  • Molecular Formula: C11H22O5
  • Molecular Weight: 234.28900
  • Catalog: Signaling Pathways Antibody-drug Conjugate ADC Linker
  • Create Date: 2016-11-21 00:16:47
  • Modify Date: 2025-08-26 14:59:02
  • Hydroxy-PEG2-(CH2)2-Boc is a uncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Hydroxy-PEG2-(CH2)2-Boc is extracted from patent WO2004008101A2 (compound 196)[1].

Name tert-butyl 3-[2-(2-hydroxyethoxy)ethoxy]propanoate
Synonyms 9-hydroxy-4,7-dioxanonanoic acid tert-butyl ester
Propanoic acid,3-[2-(2-hydroxyethoxy)ethoxy]-,1,1-dimethylethyl ester
tert-butyl 3-[di(ethylene glycol)]propanoate
tert-butyl 3-(2-(2-hydroxyethoxy)ethoxy)propanoate
Hydroxy-PEG2-t-butyl ester
Description Hydroxy-PEG2-(CH2)2-Boc is a uncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Hydroxy-PEG2-(CH2)2-Boc is extracted from patent WO2004008101A2 (compound 196)[1].
Related Catalog
Target

Non-cleavable

In Vitro ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
References

[1]. Qingqi Chen,et al. The use of isocyanate linkers to make hydrolyzable active agent biopolymer conjugates. Patent WO2004008101A2.

Molecular Formula C11H22O5
Molecular Weight 234.28900
Exact Mass 234.14700
PSA 64.99000
LogP 0.74370
Precursor  2

DownStream  0

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