Hydroxy-PEG2-(CH2)2-Boc

Modify Date: 2024-01-04 12:10:43

Hydroxy-PEG2-(CH2)2-Boc Structure
Hydroxy-PEG2-(CH2)2-Boc structure
Common Name Hydroxy-PEG2-(CH2)2-Boc
CAS Number 133803-81-3 Molecular Weight 234.28900
Density N/A Boiling Point N/A
Molecular Formula C11H22O5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Hydroxy-PEG2-(CH2)2-Boc


Hydroxy-PEG2-(CH2)2-Boc is a uncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Hydroxy-PEG2-(CH2)2-Boc is extracted from patent WO2004008101A2 (compound 196)[1].

 Names

Name tert-butyl 3-[2-(2-hydroxyethoxy)ethoxy]propanoate
Synonym More Synonyms

 Hydroxy-PEG2-(CH2)2-Boc Biological Activity

Description Hydroxy-PEG2-(CH2)2-Boc is a uncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Hydroxy-PEG2-(CH2)2-Boc is extracted from patent WO2004008101A2 (compound 196)[1].
Related Catalog
Target

Non-cleavable

In Vitro ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
References

[1]. Qingqi Chen,et al. The use of isocyanate linkers to make hydrolyzable active agent biopolymer conjugates. Patent WO2004008101A2.

 Chemical & Physical Properties

Molecular Formula C11H22O5
Molecular Weight 234.28900
Exact Mass 234.14700
PSA 64.99000
LogP 0.74370

 Precursor & DownStream

Precursor  2

DownStream  0

 Synonyms

9-hydroxy-4,7-dioxanonanoic acid tert-butyl ester
Propanoic acid,3-[2-(2-hydroxyethoxy)ethoxy]-,1,1-dimethylethyl ester
tert-butyl 3-[di(ethylene glycol)]propanoate
tert-butyl 3-(2-(2-hydroxyethoxy)ethoxy)propanoate
Hydroxy-PEG2-t-butyl ester
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