198277-54-2

198277-54-2 structure

Name: Tyr-α-CGRP (23-37) (mouse, rat)
Chemical Name: h-tyr-val-lys-asp-asn-phe-val-pro-thr-asn-val-gly-ser-glu-ala-phe-nh2
CAS Number: 198277-54-2
Molecular Formula: C₈₂H₁₂₀N₂₀O₂₅
Molecular Weight: 1785.95000
Catalog: Signaling Pathways GPCR/G Protein Adenylate Cyclase
Create Date: 2017-03-28 12:44:34
Modify Date: 2025-08-25 13:21:20
[Tyr22] Calcitonin Gene Related Peptide, (22-37), rat is a fragments 22-37 of rat calcitonin gene related peptide (CGRP), targeting CGRP receptor and adenylate cyclase. Calcitonin is mainly produced by thyroid C cells while CGRP is secreted and stored in the nervous system[1].

Name	h-tyr-val-lys-asp-asn-phe-val-pro-thr-asn-val-gly-ser-glu-ala-phe-nh2
Synonyms	yvkdnfvptnvgseaf-nh2 Tyr-α-CGRP (23-37) (mouse, rat) [Tyr22]-a-CGRP (22-37),rat

Description	[Tyr22] Calcitonin Gene Related Peptide, (22-37), rat is a fragments 22-37 of rat calcitonin gene related peptide (CGRP), targeting CGRP receptor and adenylate cyclase. Calcitonin is mainly produced by thyroid C cells while CGRP is secreted and stored in the nervous system[1].
Related Catalog	Signaling Pathways >> GPCR/G Protein >> CGRP Receptor Signaling Pathways >> Neuronal Signaling >> CGRP Receptor Research Areas >> Others Signaling Pathways >> GPCR/G Protein >> Adenylate Cyclase
In Vitro	Calcitonin Gene Related Peptide (CGRP) in humans, exists in two forms: CGRP alpha (α-CGRP or CGRP I), and CGRP beta (β-CGRP or CGRP II)[2]. [Tyr22] Calcitonin Gene Related Peptide, (22-37), rat shows the receptor binding affinity mainly depending on the carboxyterminal end while the ability to stimulate adenylate cyclase (AC) enzyme mainly depending on the aminoterminal end[3].