86649-84-5

86649-84-5 structure

Name: Tyr-Somatostatin-28
Chemical Name: 37-[[2-[2-[[6-amino-2-[[2-[[2-[[2-[[1-[2-[[2-[2-[[1-[4-amino-2-[[2-[[4-amino-2-[2-[[2-[[2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-3-hydroxy-propanoyl]amino]propanoylamino]-4-oxo-butanoyl]amino]-3-hydroxy-propanoyl]amino]-4-oxo-butanoyl]pyrrolidine-2-carbonyl]amino]propanoylamino]-4-methylsulfanyl-butanoyl]amino]propanoyl]pyrrolidine-2-carbonyl]amino]-5-guanidino-pentanoyl]amino]-4-carboxy-butanoyl]amino]-5-guanidino-pentanoyl]amino]hexanoyl]amino]propanoylamino]acetyl]amino]-19,34-bis(4-aminobutyl)-31-(2-amino-2-oxo-ethyl)-13,25,28-tribenzyl-10,16-bis(1-hydroxyethyl)-7-(hydroxymethyl)-22-(1H-indol-3-ylmethyl)-6,9,12,15,18,21,24,27,30,33,36-undecaoxo-1,2-dithia-5,8,11,14,17,20,23,26,29,32,35-undecazacyclooctatriacontane-4-carboxylic acid
CAS Number: 86649-84-5
Molecular Formula: C₁₄₆H₂₁₆N₄₂O₄₁S₃
Molecular Weight: 3311.73000
Catalog: Signaling Pathways Membrane Transporter/Ion Channel Potassium Channel
Create Date: 2018-12-31 19:14:19
Modify Date: 2024-03-03 03:40:46
Tyr-Somatostatin-28 is a somatostatin that adds a Tyrosine amino acid to Somatostatin-28[1].

Name	37-[[2-[2-[[6-amino-2-[[2-[[2-[[2-[[1-[2-[[2-[2-[[1-[4-amino-2-[[2-[[4-amino-2-[2-[[2-[[2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-3-hydroxy-propanoyl]amino]propanoylamino]-4-oxo-butanoyl]amino]-3-hydroxy-propanoyl]amino]-4-oxo-butanoyl]pyrrolidine-2-carbonyl]amino]propanoylamino]-4-methylsulfanyl-butanoyl]amino]propanoyl]pyrrolidine-2-carbonyl]amino]-5-guanidino-pentanoyl]amino]-4-carboxy-butanoyl]amino]-5-guanidino-pentanoyl]amino]hexanoyl]amino]propanoylamino]acetyl]amino]-19,34-bis(4-aminobutyl)-31-(2-amino-2-oxo-ethyl)-13,25,28-tribenzyl-10,16-bis(1-hydroxyethyl)-7-(hydroxymethyl)-22-(1H-indol-3-ylmethyl)-6,9,12,15,18,21,24,27,30,33,36-undecaoxo-1,2-dithia-5,8,11,14,17,20,23,26,29,32,35-undecazacyclooctatriacontane-4-carboxylic acid
Synonyms	Tyr-Somatostatin-28 Tyr-Ser-Ala-Asn-Ser-Asn-Pro-Ala-Met-Ala-Pro-Arg-Glu-Arg-Lys-Ala-Gly-Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Thr-Ser-Cys YSANSNPAMAPRERKAGCKNFFWKTFTSC

Description	Tyr-Somatostatin-28 is a somatostatin that adds a Tyrosine amino acid to Somatostatin-28[1].
Related Catalog	Research Areas >> Neurological Disease Signaling Pathways >> Membrane Transporter/Ion Channel >> Potassium Channel
In Vitro	在豚鼠原代培养的胰腺腺泡细胞的基底外侧质膜中，Insulin (Insulin (human) (HY-P0035)) 增加 Ca2+ 激活的 K+ 通道的 p 值，Tyr-Somatostatin-28 (0.3 μM) 可逆转这种情况[1]。
References	[1]. M Yanagisawa, et al. A reciprocal regulation of Ca(2+)-activated K(+) channel by insulin and somatostatin in guinea-pig pancreatic acinar cells. Jpn J Physiol. 2001 Jun;51(3):355-63.