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71627-22-0

71627-22-0 structure
71627-22-0 structure
  • Name: PIPERMETHYSTINE
  • Chemical Name: [6-oxo-1-(3-phenylpropanoyl)-2,3-dihydropyridin-3-yl] acetate
  • CAS Number: 71627-22-0
  • Molecular Formula: C16H17NO4
  • Molecular Weight: 287.31
  • Catalog: Signaling Pathways Apoptosis Apoptosis
  • Create Date: 2017-10-19 09:52:32
  • Modify Date: 2024-01-10 15:40:50
  • Pipermethystine is an alkaloid that can be isolated from the Kava plant. Pipermethystine decreases HepG2 cell cellular ATP levels, mitochondrial membrane potential, and induces apoptosis[1].

Name [6-oxo-1-(3-phenylpropanoyl)-2,3-dihydropyridin-3-yl] acetate
Synonyms (+/-)-5-acetoxy-5,6-dihydro-N-(1-oxo-3-phenylpropyl)-2(1H)-pyridone
Pipermethistin
2(1H)-Pyridinone,5-(acetyloxy)-5,6-dihydro-1-(1-oxo-3-phenylpropyl)
6-Oxo-1-(3-phenylpropanoyl)-1,2,3,6-tetrahydro-3-pyridinyl acetate
(+/-)-pipermethystine
5-acetoxy-1-(3-phenyl-propionyl)-5,6-dihydro-1H-pyridin-2-one
Description Pipermethystine is an alkaloid that can be isolated from the Kava plant. Pipermethystine decreases HepG2 cell cellular ATP levels, mitochondrial membrane potential, and induces apoptosis[1].
Related Catalog
References

[1]. Nerurkar PV, et al. In vitro toxicity of kava alkaloid, pipermethystine, in HepG2 cells compared to kavalactones. Toxicol Sci. 2004 May;79(1):106-11.  

Density 1.23g/cm3
Boiling Point 459.9ºC at 760 mmHg
Molecular Formula C16H17NO4
Molecular Weight 287.31
Flash Point 231.9ºC
Exact Mass 287.11600
PSA 63.68000
LogP 1.41380
Index of Refraction 1.574

~98%

71627-22-0 structure

71627-22-0

Literature: Arrayas; Alcudia; Liebeskind Organic letters, 2001 , vol. 3, # 21 p. 3381 - 3383

~%

71627-22-0 structure

71627-22-0

Literature: Arrayas; Alcudia; Liebeskind Organic letters, 2001 , vol. 3, # 21 p. 3381 - 3383

~%

71627-22-0 structure

71627-22-0

Literature: Arrayas; Alcudia; Liebeskind Organic letters, 2001 , vol. 3, # 21 p. 3381 - 3383

~%

71627-22-0 structure

71627-22-0

Literature: Arrayas; Alcudia; Liebeskind Organic letters, 2001 , vol. 3, # 21 p. 3381 - 3383

~%

71627-22-0 structure

71627-22-0

Literature: Arrayas; Alcudia; Liebeskind Organic letters, 2001 , vol. 3, # 21 p. 3381 - 3383