77529-42-1

77529-42-1 structure
77529-42-1 structure
  • Name: Glycolic acid oxidase inhibitor 1
  • Chemical Name: 3-[4-(4-bromophenyl)phenyl]-4-hydroxypyrrole-2,5-dione
  • CAS Number: 77529-42-1
  • Molecular Formula: C16H10BrNO3
  • Molecular Weight: 344.16000
  • Catalog: Research Areas Metabolic Disease
  • Create Date: 2016-10-23 09:48:11
  • Modify Date: 2024-01-09 21:20:11
  • Glycolic acid oxidase inhibitor 1 is a glycolate oxidase inhibitor, extracted from patent EP0021228A1, in Table IV.

Name 3-[4-(4-bromophenyl)phenyl]-4-hydroxypyrrole-2,5-dione
Synonyms Glycolic acid oxidase inhibitor 1
Description Glycolic acid oxidase inhibitor 1 is a glycolate oxidase inhibitor, extracted from patent EP0021228A1, in Table IV.
Related Catalog
Target

Glycolate oxidase[1]

In Vivo Glycolic acid oxidase inhibitor 1 inhibits oxalate biosynthesis in isolated perfused rat liver. Glycolate oxidase inhibitors provide a specific approach to the prevention and treatment of calcium oxalate renal lithiasis[1].
References

[1]. Cragoe Jr., Edward J, et al. 4-Substituted-3-hydroxy-3-pyrroline-2,5-dione compounds, process for their preparation and pharmaceutical compositions containing the same.EP0021228A1.

Density 1.641g/cm3
Boiling Point 528.9ºC at 760 mmHg
Molecular Formula C16H10BrNO3
Molecular Weight 344.16000
Flash Point 273.7ºC
Exact Mass 342.98400
PSA 69.89000
LogP 3.31750
Index of Refraction 1.688
Storage condition 2-8℃