93673-82-6

93673-82-6 structure

Name: Hydroxy-PEG1-C2-methyl ester
Chemical Name: methyl 3-(2-hydroxyethoxy)propanoate
CAS Number: 93673-82-6
Molecular Formula: C₆H₁₂O₄
Molecular Weight: 148.15700
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2017-04-21 06:35:44
Modify Date: 2024-01-12 11:20:59
Hydroxy-PEG1-C2-methyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	methyl 3-(2-hydroxyethoxy)propanoate

Description	Hydroxy-PEG1-C2-methyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs Alkyl/ether
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562