66791-71-7
66791-71-7 structure
- Name: 1-epi-Calcitriol
- Chemical Name: [3H]-1,25-Dihydroxyvitamin D3
- CAS Number: 66791-71-7
- Molecular Formula: C27H44O3
- Molecular Weight: 416.63600
- Catalog: Signaling Pathways Vitamin D Related VD/VDR
- Create Date: 2018-05-18 08:00:00
- Modify Date: 2026-07-04 10:13:53
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Impurity B of Calcitriol, Calcitriol(1,25-Dihydroxyvitamin D3; Rocaltrol ) is the hormonally active form of vitamin D, Calcitriol is the active metabolite of vitamin D3 that activates the vitamin D receptor (VDR).IC50 value:Target: vitamin D receptorCalcitriol(1,25-Dihydroxyvitamin D3; Rocaltrol ) displays calcemic actions. Calcitriol stimulates intestinal and renal Ca2+ absorption and regulates bone Ca2+ turnover. Calcitriol (1,25-Dihydroxyvitamin D3; Rocaltrol )exhibits antitumor activity; Calcitriol(1,25-Dihydroxyvitamin D3; Rocaltrol ) inhibits in vivo and in vitro cell proliferation in a wide range of cells including breast, prostate, colon, skin and brain carcinomas and myeloid leukemia cells.
| Name | [3H]-1,25-Dihydroxyvitamin D3 |
|---|---|
| Synonyms |
IMpurity B of Calcitriol
EPI-CALCITRIOL Calcitriol Impurity B i-Calcitriol) Calcitriol Impurity 2 1,3-Cyclohexanediol, 4-methylene-5-[(2E)-2-[(1R,3aS,4E,7-octahydro-1-[(1R)-5-hydroxy-1,5-dimethylhexyl]-7a-methyl-4H-inden-4-ylidene]ethylidene]-, (1R,3R) 1-Epicalcitriol Calcitriol impurity B 1-i-Calcitriol 1,25-Dihydroxy Vitamin D3 Impurity B 1β-Calcitriol Calcitriol Impurity B/i-Calcitriol/(1R,3R,Z)-5-(2-((1R,3aS,7,E)-1-((R)-6-Hydroxy-6-methylhtan-2-yl)-7a-methyloctahydro-4H-inden-4-ylidene)ethylidene)-4-methylenecyclohexane-1,3-diol (1R,3R,Z)-5-((E)-2-((1R,3aS,7-1-((R)-6-hydroxy-6-Methylhtan-2-yl)-7a-Methylhexahydro-1H-inden-4(2H)-ylidene)ethylidene)-4-Methylenecyclohexane-1,3-diol Calcitriol Impurity 2(Calcitriol Impurity B) 1beta,25-Dihydroxyvitamin-D3 1β,25-Dihydroxyvitamin-D3 NS 8 Impurity B of Calcitrio i-Calcitriol 1beta,25-Dihydroxycholecalciferol Rocaltrol Impurity B |
| Description | Impurity B of Calcitriol, Calcitriol(1,25-Dihydroxyvitamin D3; Rocaltrol ) is the hormonally active form of vitamin D, Calcitriol is the active metabolite of vitamin D3 that activates the vitamin D receptor (VDR).IC50 value:Target: vitamin D receptorCalcitriol(1,25-Dihydroxyvitamin D3; Rocaltrol ) displays calcemic actions. Calcitriol stimulates intestinal and renal Ca2+ absorption and regulates bone Ca2+ turnover. Calcitriol (1,25-Dihydroxyvitamin D3; Rocaltrol )exhibits antitumor activity; Calcitriol(1,25-Dihydroxyvitamin D3; Rocaltrol ) inhibits in vivo and in vitro cell proliferation in a wide range of cells including breast, prostate, colon, skin and brain carcinomas and myeloid leukemia cells. |
|---|---|
| Related Catalog | |
| References |
[2]. Calcitriol in cancer treatment: from the lab to the clinic. Mol.Cancer Ther. 3 373. |
| Molecular Formula | C27H44O3 |
|---|---|
| Molecular Weight | 416.63600 |
| Exact Mass | 416.32900 |
| PSA | 60.69000 |
| LogP | 5.70470 |
| Storage condition | 2-8℃ |
| Precursor 6 | |
|---|---|
| DownStream 0 | |
