66791-71-7

66791-71-7结构式

中文名	表骨化三醇
英文名	[3H]-1,25-Dihydroxyvitamin D3
中文别名	1Β,25-二羟基维他命 D3 6'-胞苷酸杂质骨化三醇杂质B(表骨化三醇) I-骨化三醇 GHC-Z01GHC-Z01(1Β-骨化三醇) 1Β-骨化三醇钙三醇杂质B 骨化三醇杂质2(骨化三醇杂质B) 1beta,25-二羟基维他命-D3 1BETA,25-二羟基维他命-D3 骨化三醇杂质B 1-表骨化三醇 1-表钙三醇
英文别名	IMpurity B of Calcitriol EPI-CALCITRIOL Calcitriol Impurity B i-Calcitriol) Calcitriol Impurity 2 1,3-Cyclohexanediol, 4-methylene-5-[(2E)-2-[(1R,3aS,4E,7-octahydro-1-[(1R)-5-hydroxy-1,5-dimethylhexyl]-7a-methyl-4H-inden-4-ylidene]ethylidene]-, (1R,3R) 1-Epicalcitriol Calcitriol impurity B 1-i-Calcitriol 1,25-Dihydroxy Vitamin D3 Impurity B 1β-Calcitriol Calcitriol Impurity B/i-Calcitriol/(1R,3R,Z)-5-(2-((1R,3aS,7,E)-1-((R)-6-Hydroxy-6-methylhtan-2-yl)-7a-methyloctahydro-4H-inden-4-ylidene)ethylidene)-4-methylenecyclohexane-1,3-diol (1R,3R,Z)-5-((E)-2-((1R,3aS,7-1-((R)-6-hydroxy-6-Methylhtan-2-yl)-7a-Methylhexahydro-1H-inden-4(2H)-ylidene)ethylidene)-4-Methylenecyclohexane-1,3-diol Calcitriol Impurity 2(Calcitriol Impurity B) 1beta,25-Dihydroxyvitamin-D3 1β,25-Dihydroxyvitamin-D3 NS 8 Impurity B of Calcitrio i-Calcitriol 1beta,25-Dihydroxycholecalciferol Rocaltrol Impurity B

描述	Impurity B of Calcitriol是Calcitriol的杂质,Calcitriol是维生素D3的活性代谢物,能激活维生素D受体。
相关类别	信号通路 >> 维生素 D 相关 >> VD/VDR 研究领域 >> 癌症
参考文献	[1]. Canalejo et al (2000) The in vitro effect of calcitriol on parathyroid cell proliferation and apoptosis. J.Am.Soc.Nephrol. 11 1865. Beer and Myrthue (2004) [2]. Calcitriol in cancer treatment: from the lab to the clinic. Mol.Cancer Ther. 3 373. [3]. Krishnan AV, Swami S, Feldman D.Equivalent anticancer activities of dietary vitamin D and calcitriol in an animal model of breast cancer: Importance of mammary CYP27B1 for treatment and prevention.J Steroid Biochem Mol Biol. 2012 Aug 23. [4]. Alkharfy KM, Al-Daghri NM, Yakout SM, Ahmed M. Calcitriol Attenuates Weight-Related Systemic Inflammation and Ultrastructural Changes of the Liver in a Rodent Model.Basic Clin Pharmacol Toxicol. 2012 Aug 21.