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62265-68-3

62265-68-3 structure

62265-68-3 structure

Name: Quinfamide
Chemical Name: [1-(2,2-dichloroacetyl)-3,4-dihydro-2H-quinolin-6-yl] furan-2-carboxylate
CAS Number: 62265-68-3
Molecular Formula: C₁₆H₁₃Cl₂NO₄
Molecular Weight: 354.18
Catalog: Signaling Pathways Anti-infection Parasite
Create Date: 2018-06-07 15:17:30
Modify Date: 2026-07-16 17:12:06
Quinfamide is an antiamebic agent. Quinfamide can be used to treat tropical parasitic infections such as Amoebiasis and Helminthiasis[1].

Name	[1-(2,2-dichloroacetyl)-3,4-dihydro-2H-quinolin-6-yl] furan-2-carboxylate
Synonyms	Win-40014 1-(Dichloroacetyl)-6-(2-furoyloxy)-1,2,3,4-tetrahydro-6-quinoline 1-(dichloroacetyl)-6-(2-furoyloxy)-1,2,3,4-tetrahydroquinoline 4-amino-N-(4-oxo-5,6,7,8-tetrahydro-1H-quinazolin-2-yl)benzenesulfonamide Quinfamide (WIN-40014) Quinfamide, 10 mM in DMSO 1-(2,2-Dichloroacetyl)-1,2,3,4-tetrahydroquinolin-6-yl furan-2-cboxylate AMenide AMenox Quinfamido [INN-Spanish] Amenide EINECS 263-478-1 quinfamide QUINTAMIDE Quinfamidum [INN-Latin] 2-Furancboxylic Acid 1-(2,2-Dichloroacetyl)-1,2,3,4-tetrahydro-6-quinolinyl Ester 1-(dichloroacetyl)-1,2,3,4-tetrahydroquinolin-6-yl 2-furoate 1-(Dichloroacetyl)-6-(2-furoyloxy)-1,2,3,4-tetrahydroquinoline 2-Furancboxylic acid 1-(dichloroacetyl)-1,2,3,4-tetrahydroquinolin-6-yl ester inhibit,Pasite,WIN40014,Quinfamide,Inhibitor,WIN

Description	Quinfamide is an antiamebic agent. Quinfamide can be used to treat tropical parasitic infections such as Amoebiasis and Helminthiasis[1].
Related Catalog	Signaling Pathways >> Anti-infection >> Parasite Research Areas >> Infection
References	[1]. Davila-Gutierrez CE, et al. Nitazoxanide compared with quinfamide and mebendazole in the treatment of helminthic infections and intestinal protozoa in children. Am J Trop Med Hyg. 2002 Mar;66(3):251-4.

Density	1.428g/cm3
Boiling Point	551.3ºC at 760mmHg
Melting Point	145-146ºC
Molecular Formula	C₁₆H₁₃Cl₂NO₄
Molecular Weight	354.18
Flash Point	287.2ºC
Exact Mass	353.02200
PSA	59.75000
LogP	3.64670
Index of Refraction	1.599
Storage condition	2-8°C

CHEMICAL IDENTIFICATION

RTECS NUMBER :: LU0215000

CHEMICAL NAME :: 2-Furancarboxylic acid, 1-(dichloroacetyl)-1,2,3,4-tetrahydro-6-quinolinyl ester

CAS REGISTRY NUMBER :: 62265-68-3

LAST UPDATED :: 199612

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C16-H13-Cl2-N-O4

MOLECULAR WEIGHT :: 354.20

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD - Lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >10 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 22,599,1979

TYPE OF TEST :: LD - Lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - hamster

DOSE/DURATION :: >10 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 22,599,1979

HS Code	2934999090

527-69-5 structure

527-69-5

62265-67-2 structure

62265-67-2

7440-44-0 structure

7440-44-0

~%

62265-68-3 structure

62265-68-3

Literature: US3997542 A1, ;

HS Code	2934999090
Summary	2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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