1852-36-4

1852-36-4 structure

Name: Cortisol sulfate sodium
Chemical Name: hydrocortisone 21-(sodium sulphate)
CAS Number: 1852-36-4
Molecular Formula: C₂₁H₂₉NaO₈S
Molecular Weight: 464.50
Catalog: Research Areas Endocrinology
Create Date: 2017-06-10 12:57:31
Modify Date: 2025-08-28 21:41:01
Cortisol sulfate sodium (Cortisol 21-sulfate) is a metabolite of Cortisol (HY-N0583). Cortisol sulfate sodium is a specific ligand for intracellular transcortin[1][2][3].

Name	hydrocortisone 21-(sodium sulphate)
Synonyms	Corticosterone acetate 4-Pregnene-11beta,21-diol-3,20-dione 21-acetate Cort A 11beta,21-Dihydroxy-4-pregnene-3,20-dione 21-acetate 2-((8S,9S,10R,11S,13S,14S,17S)-11-hydroxy-10,13-dimethyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)-2-oxoethyl acetate Hydrocortisone-21-sulfatesodium Cortisol-21-sulfat 11beta,21-Dihydroxypregn-4-ene-3,20-dione 21-acetate Corticosterone 21-acetate

Description	Cortisol sulfate sodium (Cortisol 21-sulfate) is a metabolite of Cortisol (HY-N0583). Cortisol sulfate sodium is a specific ligand for intracellular transcortin[1][2][3].
Related Catalog	Research Areas >> Endocrinology
In Vivo	Cortisol sulfate sodium (3 mg; i.m.; every other day; for 2-7 weeks) affects behavior through its direct action on the central nervous system[4].
References	[1]. C S Hall, et al. Simultaneous metabolism of cortisol sulfate and cortisol in normal human adults. J Clin Endocrinol Metab. 1970 Oct;31(4):439-44. [2]. S S Singer, et al. Enzymatic sulfation of steroids: I. The enzymatic basis for the sex difference in cortisol sulfation by rat liver preparations. Endocrinology. 1976 Apr;98(4):963-74. [3]. T Hayashi, et al. Cortisol-21-sulfate (FS) is a specific ligand for intracellular transcortin: demonstration of three types of high affinity corticosteroid binders in bovine aortic cytosol by a combined use of FS and RU 28362. Endocrinology. 1990 Jan;126(1):307-16. [4]. S Miyabo, et al. Behavioral and other systemic effects of cortisol-21 sulfate. Horm Behav. 1972 Sep;3(3):227-36.