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3445-11-2

3445-11-2 structure
3445-11-2 structure
  • Name: 1-(2-Hydroxyethyl)-2-pyrrolidinone
  • Chemical Name: 1-(2-hydroxyethyl)pyrrolidin-2-one
  • CAS Number: 3445-11-2
  • Molecular Formula: C6H11NO2
  • Molecular Weight: 129.157
  • Create Date: 2018-03-12 08:00:00
  • Modify Date: 2024-01-02 11:47:18

Name 1-(2-hydroxyethyl)pyrrolidin-2-one
Synonyms N-(2-Hydroxyethyl)-2-pyrrolidone
1-(2-Hydroxyethyl)-2-Pyrrolidone
1-(2-hydroxyethyl)pyrrolidin-2-one
N-(2-hydroxyethyl)-2-oxo-pyrrolidine
EINECS 222-359-4
N-(2-hydroxyethyl)-pyrrolidinone
N-2-Hydroxyethylpyrrolidin-2-one
N-(2-hydroxyethyl)-2-pyrrolidinone
1-(2-Hydroxyethyl)-2-pyrrolidinone
2-Pyrrolidinone,1-(2-hydroxyethyl)
2-Pyrrolidinone, 1-(2-hydroxyethyl)-
MFCD00014103
Density 1.2±0.1 g/cm3
Boiling Point 296.0±13.0 °C at 760 mmHg
Melting Point 19-21°C
Molecular Formula C6H11NO2
Molecular Weight 129.157
Flash Point 132.8±19.8 °C
Exact Mass 129.078979
PSA 40.54000
LogP -1.02
Vapour Pressure 0.0±1.4 mmHg at 25°C
Index of Refraction 1.505
Stability Stable. Incompatible with strong oxidizing agents

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UY5776500
CHEMICAL NAME :
2-Pyrrolidinone, 1-(2-hydroxyethyl)-
CAS REGISTRY NUMBER :
3445-11-2
BEILSTEIN REFERENCE NO. :
0112181
LAST UPDATED :
199710
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C6-H11-N-O2
MOLECULAR WEIGHT :
129.18

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration into the eye
SPECIES OBSERVED :
Rodent - rabbit
REFERENCE :
EPASR* United States Environmental Protection Agency, Office of Pesticides and Toxic Substances. (U.S. Environmental Protection Agency, 401 M St., SW, Washington, DC 20460) History unknown. Volume(issue)/page/year: 8EHQ-0682-0448S ** ACUTE TOXICITY DATA **
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
14430 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
EPASR* United States Environmental Protection Agency, Office of Pesticides and Toxic Substances. (U.S. Environmental Protection Agency, 401 M St., SW, Washington, DC 20460) History unknown. Volume(issue)/page/year: 8EHQ-0682-0448S
Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes Xi:Irritant
Risk Phrases R36/37/38
Safety Phrases S26-S36
RIDADR NONH for all modes of transport
WGK Germany 2
RTECS UY5776500
HS Code 2933790090

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Literature: Ito, Masato; Ootsuka, Takashi; Watari, Ryo; Shiibashi, Akira; Himizu, Akio; Ikariya, Takao Journal of the American Chemical Society, 2011 , vol. 133, # 12 p. 4240 - 4242

~87%

3445-11-2 structure

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Literature: Lisina, N. I.; Chernov, G. A.; Bizunov, Yu. M.; Emel'yanov, V. I.; Knunyants, I. L. Pharmaceutical Chemistry Journal, 1988 , vol. 22, # 6 p. 472 - 476 Khimiko-Farmatsevticheskii Zhurnal, 1988 , vol. 22, # 6 p. 705 - 710

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Literature: US4420620 A1, ;

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Literature: Justus Liebigs Annalen der Chemie, , vol. 596, p. 1,201

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Literature: Tetrahedron, , vol. 45, # 19 p. 6161 - 6170

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3445-11-2

Literature: Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, , p. 111; engl. Ausg. S. 109

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3445-11-2

Literature: Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, , p. 111; engl. Ausg. S. 109
HS Code 2933790090
Summary 2933790090. other lactams. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:9.0%. General tariff:20.0%