131084-35-0
131084-35-0 structure
- Name: CP-94,253
- Chemical Name: 5-propoxy-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-pyrrolo[3,2-b]pyridine,hydrochloride
- CAS Number: 131084-35-0
- Molecular Formula: C15H20ClN3O
- Molecular Weight: 257.331
- Create Date: 2018-06-25 13:44:30
- Modify Date: 2025-08-25 13:19:41
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CP-94,253 is a potent and selective serotonin 5-HT1B receptor agonist with approximately 25x and 40x selectivity over the closely related 5-HT1D and 5-HT1A receptors. Ki values are 89, 2, 860, 49 and 1,600 nM for 5-HT1A, 5-HT1B, 5-HT1C, 5-HT1D and 5-HT2 receptors respectively. CP-94,253 was found to be anxiolytic in animal models; dose-dependently enhanced reinforcing effects of cocaine (self-administration);and reduced food intake.
| Name | 5-propoxy-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-pyrrolo[3,2-b]pyridine,hydrochloride |
|---|---|
| Synonyms |
1H-Pyrrolo[3,2-b]pyridine, 5-propoxy-3-(1,2,3,6-tetrahydro-4-pyridinyl)-
CP-94,253 dihydrochloride 5-Propoxy-3-(1,2,3,6-tetrahydro-4-pyridinyl)-1H-pyrrolo[3,2-b]pyridine CP-94,253 ZLD0678 CP94253 hydrochloride |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 442.9±45.0 °C at 760 mmHg |
| Molecular Formula | C15H20ClN3O |
| Molecular Weight | 257.331 |
| Flash Point | 221.7±28.7 °C |
| Exact Mass | 257.152802 |
| PSA | 49.94000 |
| LogP | 2.69 |
| Vapour Pressure | 0.0±1.1 mmHg at 25°C |
| Index of Refraction | 1.613 |
| Hazard Codes | Xi |
|---|---|
| Risk Phrases | 22-36/37/38 |
| HS Code | 2933990090 |
| HS Code | 2933990090 |
|---|---|
| Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |