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87860-39-7

87860-39-7 structure
87860-39-7 structure
  • Name: Fostriecin
  • Chemical Name: Fostriecin sodium salt,(6R)-5,6-Dihydro-6-[(1E,3R,4R,6R,7Z,9Z,11E)-3,6,13-trihydroxy-3-methyl-4-(phosphonooxy)-1,7,9,11-tridecatetraenyl]-2H-pyran-2-onesodiumsalt
  • CAS Number: 87860-39-7
  • Molecular Formula: C19H26NaO9P
  • Molecular Weight: 452.36800
  • Catalog: API Antibiotics Polyene
  • Create Date: 2018-02-08 08:00:00
  • Modify Date: 2024-01-02 17:04:49
  • Fostriecin is an inhibitor of the serine/threonine protein phosphatases 2A (PP2A) and 4 (PP4)

Name Fostriecin sodium salt,(6R)-5,6-Dihydro-6-[(1E,3R,4R,6R,7Z,9Z,11E)-3,6,13-trihydroxy-3-methyl-4-(phosphonooxy)-1,7,9,11-tridecatetraenyl]-2H-pyran-2-onesodiumsalt
Synonyms PHOSPHOTRIENIN
FOSTRIECIN SODIUM SALT
cl1565asodiumsalt
FOSTRIECIN
FST
antibioticcl1565asodiumsalt
MFCD01939908
FOSTRIECIN SODIUM
CL-920
ci920sodiumsalt
antibioticci920sodiumsalt
Boiling Point 737.9ºC at 760 mmHg
Molecular Formula C19H26NaO9P
Molecular Weight 452.36800
Flash Point 400.1ºC
Exact Mass 452.12100
PSA 166.39000
LogP 1.49330
Storage condition −20°C

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UQ0600000
CHEMICAL NAME :
2H-Pyran-2-one, 5,6-dihydro-6-(3,6,13-trihydroxy-3-methyl-4-(phosphon ooxy)-1,7,9,11- tridecatetraenyl)-, monosodium salt
CAS REGISTRY NUMBER :
87860-39-7
LAST UPDATED :
199606
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C19-H27-O9-P.Na

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
100 mg/kg
TOXIC EFFECTS :
Tumorigenic - active as anti-cancer agent
REFERENCE :
EJCODS European Journal of Cancer and Clinical Oncology. (Pergamon Press, c/o Elsevier Science, 660 White Plains Rd., Tarrytown, NY 10591) V.17(7)- 25, 1981-89. For publisher information, see EJCAEL Volume(issue)/page/year: 22,921,1986
Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS UQ0600000