32222-00-7

32222-00-7 structure

Name: (Tyr8)-Bradykinin
Chemical Name: arg-pro-pro-gly-phe-ser-pro-tyr-arg
CAS Number: 32222-00-7
Molecular Formula: C₅₀H₇₃N₁₅O₁₂
Molecular Weight: 1076.21000
Catalog: Signaling Pathways GPCR/G Protein Bradykinin Receptor
Create Date: 2018-12-24 13:32:07
Modify Date: 2026-07-30 08:58:52
[Tyr8] Bradykinin is a B2 kinin receptor agonist. [Tyr8] Bradykinin also stimulates ERK1/2 phosphorylation. [Tyr8] Bradykinin can be used as an internal standard[1].

Name	arg-pro-pro-gly-phe-ser-pro-tyr-arg
Synonyms	H-G-PRO-PRO-GLY-PHE-SER-PRO-TYR-G-OH Asp-Pro-Pro-Gly-Phe-Ser-Pro-Tyr-Arg RPPGFSPYR BRADYKININ (TYR8) Tyr8-bradykinin tyrosine8-bradykinin L-g-L-Pro-L-Pro-Gly-L-Phe-L-Ser-L-Pro-L-Tyr-L-g-OH G-PRO-PRO-GLY-PHE-SER-PRO-TYR-G L-Arg-L-Pro-L-Pro-Gly-L-Phe-L-Ser-L-Pro-L-Tyr-L-Arg-OH Bradykinin, 8-L-tyrosine (TYR8)-BRADYKININ N5-(Diaminomethylene)-L-ornithyl-L-prolyl-L-prolylglycyl-L-phenylalanyl-L-seryl-L-prolyl-L-tyrosyl-N5-(diaminomethylene)-L-ornithine

Description	[Tyr8] Bradykinin is a B2 kinin receptor agonist. [Tyr8] Bradykinin also stimulates ERK1/2 phosphorylation. [Tyr8] Bradykinin can be used as an internal standard[1].
Related Catalog	Research Areas >> Cardiovascular Disease Research Areas >> Endocrinology Signaling Pathways >> MAPK/ERK Pathway >> ERK Signaling Pathways >> GPCR/G Protein >> Bradykinin Receptor Signaling Pathways >> Stem Cell/Wnt >> ERK
Target	Bradykinin B2 Receptor (B2R) ERK1 ERK2
In Vitro	[Tyr8] Bradykinin (10 nM, 2 min) produces a rapid increase in phosphorylated ERK1/2[1]. Western Blot Analysis[1] Cell Line: Serum-deprived trabecular meshwork cells Concentration: 10 nM Incubation Time: 2 min Result: Produced a rapid increase in phosphorylated ERK1/2 that was equivalent in magnitude to that observed for Bradykinin (HY-P0206).