38989-37-6

38989-37-6 structure

38989-37-6 structure

Name: Berbinium, 5,6,7,8,13,13a-hexadehydro-2,3,10,11-tetramethoxy-8-methyl-, saltwith acetic acid
Chemical Name: Berbinium, 5,6,7,8,13,13a-hexadehydro-2,3,10,11-tetramethoxy-8-methyl-, saltwith acetic acid
CAS Number: 38989-37-6
Molecular Formula: C₂₄H₂₅NO₉S
Molecular Weight: 503.52200
Create Date: 2016-10-12 19:53:43
Modify Date: 2024-02-24 18:14:47

Name	Berbinium, 5,6,7,8,13,13a-hexadehydro-2,3,10,11-tetramethoxy-8-methyl-, saltwith acetic acid
Synonyms	2,3,9,10-Bis-dioxymethylen-protoberberin Coptisine,chloride coralyne sulphoacetate Coptisinium coptysine chloride Coralyn-sulfoacetat Coptisine HCl Coptisine hydrochloride Coptisin chlorid

Molecular Formula	C₂₄H₂₅NO₉S
Molecular Weight	503.52200
Exact Mass	503.12500
PSA	143.90000
LogP	2.77940

CHEMICAL IDENTIFICATION

RTECS NUMBER :: HQ1815000

CAS REGISTRY NUMBER :: 38989-37-6

LAST UPDATED :: 199304

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C22-H22-N-O4.C2-H3-O5-S

MOLECULAR WEIGHT :: 503.56

WISWESSER LINE NOTATION :: T D6 B666 KKJ FO1 GO1 J1 PO1 QO1 &WSQ1VQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 173 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NCISP* National Cancer Institute Screening Program Data Summary, Developmental Therapeutics Program. (Bethesda, MD 20205) Volume(issue)/page/year: JAN1986

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 221 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 37,165,1976

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Mammal - dog

DOSE/DURATION :: 37 mg/kg

TOXIC EFFECTS :: Behavioral - food intake (animal) Nutritional and Gross Metabolic - weight loss or decreased weight gain

REFERENCE :: TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 37,165,1976

Risk Phrases	25
Safety Phrases	45