Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Benzenesulfonamide,4-amino-N-2-pyrazinyl-
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

116-44-9

116-44-9 structure

Name: Benzenesulfonamide,4-amino-N-2-pyrazinyl-
Chemical Name: 4-amino-N-pyrazin-2-ylbenzenesulfonamide
CAS Number: 116-44-9
Molecular Formula: C₁₀H₁₀N₄O₂S
Molecular Weight: 250.27700
Create Date: 2016-01-05 03:56:56
Modify Date: 2024-02-04 08:20:57

Name	4-amino-N-pyrazin-2-ylbenzenesulfonamide
Synonyms	SULFAPYRAZINE 4-amino-N-pyrazin-2-yl-benzenesulfonamide 2-Sulfanilamidopyrazine sulfanilic acid pyrazin-2-ylamide N(sup 1)-2-Pyrazinylsulfonilamide Sulfanilamide,N1-(pyrazinyl) Benzenesulfonamide,4-amino-N-pyrazinyl Sulfanilsaeure-pyrazin-2-ylamid Pyrazine,sulfanilamido N1-2-Pyrazinylsulfanilamide 4-amino-N-2-pyrazinylbenzenesulfonamide 4-amino-N-pyrazinyl-benzenesulfonamide

Density	1.496g/cm3
Boiling Point	485.5ºC at 760mmHg
Molecular Formula	C₁₀H₁₀N₄O₂S
Molecular Weight	250.27700
Flash Point	247.4ºC
Exact Mass	250.05200
PSA	106.35000
LogP	2.59460
Vapour Pressure	1.41E-09mmHg at 25°C
Index of Refraction	1.679

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DA9550000

CHEMICAL NAME :: Benzenesulfonamide, 4-amino-N-pyrazinyl-

CAS REGISTRY NUMBER :: 116-44-9

BEILSTEIN REFERENCE NO. :: 0235481

LAST UPDATED :: 199612

DATA ITEMS CITED :: 5

MOLECULAR FORMULA :: C10-H10-N4-O2-S

MOLECULAR WEIGHT :: 250.30

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD - Lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >10 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 79,354,1943

TYPE OF TEST :: LD - Lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >10 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 79,354,1943

TYPE OF TEST :: LD - Lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Mammal - dog

DOSE/DURATION :: >5 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 79,354,1943 ** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 45600 mg/kg/22W-C

TOXIC EFFECTS :: Kidney, Ureter, Bladder - other changes Endocrine - thyroid weight (goiter) Related to Chronic Data - death

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 79,354,1943

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Mammal - dog

DOSE/DURATION :: 45 gm/kg/90D-C

TOXIC EFFECTS :: Liver - other changes Kidney, Ureter, Bladder - other changes

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 79,354,1943

HS Code	2935009090

5433-91-0

116-44-9

Literature: Journal of the American Chemical Society, , vol. 63, p. 3153 US2420703 , ;

14508-49-7

63-74-1

116-44-9

Literature: US2444012 , ;

121-60-8

116-44-9

Literature: Journal of the American Chemical Society, , vol. 63, p. 3153 US2420703 , ;

Precursor 4
5433-91-0 121-60-8 14508-49-7 63-74-1
DownStream 0

HS Code	2935009090
Summary	2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0%

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