4371-34-0
4371-34-0 structure
- Name: 4,4-dimethyl[1,1-biphenyl]-2,2,5,5-tetrol
- Chemical Name: 2-(2,5-dihydroxy-4-methylphenyl)-5-methylbenzene-1,4-diol
- CAS Number: 4371-34-0
- Molecular Formula: C14H14O4
- Molecular Weight: 246.25900
- Catalog: Research Areas Cancer
- Create Date: 2016-10-08 10:58:06
- Modify Date: 2024-01-14 12:42:33
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NSC2805 is a WWP2 ubiquitin ligase inhibitor that can significant inhibit WWP2 activity with an IC50 of 0.38 μM. NSC2805 can be used for the research of cancer[1].
| Name | 2-(2,5-dihydroxy-4-methylphenyl)-5-methylbenzene-1,4-diol |
|---|---|
| Synonyms |
4.4'-Dimethyl-biphenyltetrol-(2.5.2'.5')
2.5.2'.5'-Tetraoxy-4.4'-dimethyl-diphenyl 2.5.2'.5'-Tetrahydroxy-4.4'-dimethyl-biphenyl 2.5.2'.5'-Tetraoxy-ditolyl-(4.4') 4,4'-dimethyl[1,1'-biphenyl]-2,2',5,5'-tetrol 4,4'-Dimethyl-biphenyl-2,5,2',5'-tetraol |
| Description | NSC2805 is a WWP2 ubiquitin ligase inhibitor that can significant inhibit WWP2 activity with an IC50 of 0.38 μM. NSC2805 can be used for the research of cancer[1]. |
|---|---|
| Related Catalog | |
| In Vitro | NSC2805 has WWP2 inhibitory activity with an IC50 of 0.38 μM[1]. NSC2805 shows a significant reduction in activity for all three proteins (WWP2, WWP1 and Nedd4)[1]. NSC2805 can robustly inhibit WWP2-dependent PTEN ubiquitination[1]. |
| References |
| Density | 1.36g/cm3 |
|---|---|
| Boiling Point | 501.6ºC at 760 mmHg |
| Molecular Formula | C14H14O4 |
| Molecular Weight | 246.25900 |
| Flash Point | 248.2ºC |
| Exact Mass | 246.08900 |
| PSA | 80.92000 |
| LogP | 2.79280 |
| Index of Refraction | 1.675 |
| HS Code | 2906299090 |
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| HS Code | 2906299090 |
|---|---|
| Summary | 2906299090 other aromatic alcohols。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0% |