78832-61-8
78832-61-8 structure
- Name: 2-naphthol-d8
- Chemical Name: 2-naphthol-d8
- CAS Number: 78832-61-8
- Molecular Formula: C10D8O
- Molecular Weight: 152.21900
- Catalog: Research Areas Others
- Create Date: 2018-09-17 17:21:12
- Modify Date: 2024-01-02 19:22:13
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2-Naphthol-d8 is the deuterium labeled 2-Naphthol[1]. 2-Naphthol is a metabolite of naphthalene, catalyzed by cytochrome P450 (CYP) isozymes (CYP 1A1, CYP 1A2, CYP 2A1, CYP 2E1 and CYP 2F2)[2].
| Name | 2-naphthol-d8 |
|---|---|
| Synonyms |
8-azabicyclo<5.4.0>undec-1(7)-en-9-one
1,3,4,5,6,7,8,O-octadeuterio-naphthalen-2-ol 1,2,3,4,5,6,7,8-Octahydrocyclohepta[b]pyrid-2-one 1,3,4,5,6,7,8,9-octahydro-cyclohepta[b]pyridin-2-one 2H-Cyclohepta[b]pyridin-2-one,1,3,4,5,6,7,8,9-octahydro 2-Oxo-1,2,3,4-tetrahydrocycloheptano<e>pyridin |
| Description | 2-Naphthol-d8 is the deuterium labeled 2-Naphthol[1]. 2-Naphthol is a metabolite of naphthalene, catalyzed by cytochrome P450 (CYP) isozymes (CYP 1A1, CYP 1A2, CYP 2A1, CYP 2E1 and CYP 2F2)[2]. |
|---|---|
| Related Catalog | |
| In Vitro | Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1]. |
| References |
| Molecular Formula | C10D8O |
|---|---|
| Molecular Weight | 152.21900 |
| Exact Mass | 152.10800 |
| PSA | 20.23000 |
| LogP | 2.54540 |
|
~%
78832-61-8 |
| Literature: Barkanova; Kaliya; Luk'yanets Mendeleev Communications, 2001 , vol. 11, # 3 p. 116 - 118 |
| Precursor 1 | |
|---|---|
| DownStream 0 | |