6159-56-4
6159-56-4 structure
- Name: (±)-Vasicine
- Chemical Name: peganine
- CAS Number: 6159-56-4
- Molecular Formula: C11H12N2O
- Molecular Weight: 188.226
- Catalog: Signaling Pathways Membrane Transporter/Ion Channel Proton Pump
- Create Date: 2016-04-13 12:27:20
- Modify Date: 2024-01-02 21:40:54
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(±)-Vasicine is the racemate of Vasicine. Vasicine (Peganine), isolated from Peganum harmala seeds, significantly inhibits H+-K+-ATPase activity in vitro with an IC50 of 73.47 μg/mL. Anti-ulcer activity. Vasicine shows significant anti-secretory, antioxidant and cytoprotective effect[1].
| Name | peganine |
|---|---|
| Synonyms |
Pyrrolo[2,1-b]quinazolin-3-ol, 1,2,3,9-tetrahydro-, (3R)-
(3S)-1,2,3,9-Tetrahydropyrrolo[2,1-b]quinazolin-3-ol (R)-1,2,3,9-Tetrahydropyrrolo(2,1-b)quinazolin-3-ol 1,2,3,9-Tetrahydropyrrolo[2,1-b]quinazolin-3-ol (3R)-1,2,3,9-Tetrahydropyrrolo[2,1-b]quinazolin-3-ol Vasicine |
| Description | (±)-Vasicine is the racemate of Vasicine. Vasicine (Peganine), isolated from Peganum harmala seeds, significantly inhibits H+-K+-ATPase activity in vitro with an IC50 of 73.47 μg/mL. Anti-ulcer activity. Vasicine shows significant anti-secretory, antioxidant and cytoprotective effect[1]. |
|---|---|
| Related Catalog | |
| In Vitro | Vasicine (Peganine) exhibits strong antioxidant activity in the DPPH inhibition assay with an IC50 value of 71.97±3.79 μg/mL[1]. |
| References |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 373.8±52.0 °C at 760 mmHg |
| Melting Point | 211 °C |
| Molecular Formula | C11H12N2O |
| Molecular Weight | 188.226 |
| Flash Point | 179.9±30.7 °C |
| Exact Mass | 188.094955 |
| PSA | 35.83000 |
| LogP | -1.00 |
| Vapour Pressure | 0.0±0.9 mmHg at 25°C |
| Index of Refraction | 1.709 |
| RIDADR | NONH for all modes of transport |
|---|---|
| HS Code | 2933990090 |
|
~44%
6159-56-4 |
| Literature: Wasserman, Harry H.; Kuo, Gee-Hong Tetrahedron Letters, 1991 , vol. 32, # 48 p. 7131 - 7132 |
|
~%
6159-56-4 |
| Literature: Wasserman, Harry H.; Kuo, Gee-Hong Tetrahedron Letters, 1991 , vol. 32, # 48 p. 7131 - 7132 |
|
~%
6159-56-4 |
| Literature: Wasserman, Harry H.; Kuo, Gee-Hong Tetrahedron Letters, 1991 , vol. 32, # 48 p. 7131 - 7132 |
|
~%
6159-56-4 |
| Literature: Spaeth; Platzer Chemische Berichte, 1936 , vol. 69, p. 255,257 |
|
~%
6159-56-4 |
| Literature: Southwick; Casanova Journal of the American Chemical Society, 1958 , vol. 80, p. 1168,1173 |
|
~%
6159-56-4 |
| Literature: Southwick; Casanova Journal of the American Chemical Society, 1958 , vol. 80, p. 1168,1173 |
|
~%
6159-56-4 |
| Literature: Spaeth; Platzer Chemische Berichte, 1936 , vol. 69, p. 255,257 |
| Precursor 8 | |
|---|---|
| DownStream 5 | |
| HS Code | 2933990090 |
|---|---|
| Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |