128300-15-2

128300-15-2 structure

Name: (+)-CBI-CDPI2
Chemical Name: 7-{[8-{[(1aS,9bR)-5-Oxo-1a,2-dihydro-1H-benzo[e]cyclopropa[c]indo l-3(5H)-yl]carbonyl}-1,6-dihydropyrrolo[3,2-e]indol-3(2H)-yl]carb onyl}-1,6-dihydropyrrolo[3,2-e]indole-3(2H)-carboxamide
CAS Number: 128300-15-2
Molecular Formula: C₃₆H₂₈N₆O₄
Molecular Weight: 608.64500
Catalog: Signaling Pathways Antibody-drug Conjugate ADC Cytotoxin
Create Date: 2016-02-03 04:50:58
Modify Date: 2024-01-03 12:09:55
(+)-CBI-CDPI2 is an enhanced functional analog of CC-1065. (+)-CBI-CDPI1 is a DNA alkylating agent. (+)-CBI-CDPI2 is an antibody drug conjugates (ADCs) toxin.

Name	7-{[8-{[(1aS,9bR)-5-Oxo-1a,2-dihydro-1H-benzo[e]cyclopropa[c]indo l-3(5H)-yl]carbonyl}-1,6-dihydropyrrolo[3,2-e]indol-3(2H)-yl]carb onyl}-1,6-dihydropyrrolo[3,2-e]indole-3(2H)-carboxamide
Synonyms	(+)-CBI-CDPI2 (+-)-Carvotanacetol-acetat 2-Cyclohexen-1-ol,2-methyl-5-(1-methylethyl)-,acetate

Description	(+)-CBI-CDPI2 is an enhanced functional analog of CC-1065. (+)-CBI-CDPI1 is a DNA alkylating agent. (+)-CBI-CDPI2 is an antibody drug conjugates (ADCs) toxin.
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Antibody-drug Conjugate >> ADC Cytotoxin Signaling Pathways >> Cell Cycle/DNA Damage >> DNA Alkylator/Crosslinker
References	[1]. Boger DL, et al. Molecular basis for sequence selective DNA alkylation by (+)- and ent-(-)-CC-1065 and related agents: alkylation site models that accommodate the offset AT-rich adenine N3 alkylation selectivity. Bioorg Med Chem. 1994 Feb;2(2):115-35.