146-04-3

146-04-3 structure

Name: Oosponol
Chemical Name: 8-hydroxy-4-(2-hydroxyacetyl)isochromen-1-one
CAS Number: 146-04-3
Molecular Formula: C₁₁H₈O₅
Molecular Weight: 220.18
Catalog: Signaling Pathways Anti-infection Fungal
Create Date: 2018-06-11 15:26:51
Modify Date: 2025-09-13 14:04:01
Oosponol is a dopamine beta-hydroxylase inhibitor exhibiting hypotensive effects.Oospongol has strong antifungal activity against many antagonistic fungi[1][2].

Name	8-hydroxy-4-(2-hydroxyacetyl)isochromen-1-one
Synonyms	4-glycoloyl-8-hydroxy-1H-isochromen-1-one Lezitin=Oosponol Lenzitin 8-Hydroxy-4-(hydroxyacetyl)-1H-2-benzopyran-1-one ISOCOUMARIN,4-GLYCOLYL-8-HYDROXY 8-hydroxy-4-hydroxyacetyl-isochromen-1-one Oosponol 4-Glycolyl-8-hydroxy-isocoumarin

Description	Oosponol is a dopamine beta-hydroxylase inhibitor exhibiting hypotensive effects.Oospongol has strong antifungal activity against many antagonistic fungi[1][2].
Related Catalog	Research Areas >> Cardiovascular Disease Research Areas >> Infection Signaling Pathways >> Anti-infection >> Fungal
References	[1]. Umezawa H, et al.. Dopamine -hydroxylase inhibitor produced by Gloeophyllum striatum and its identity with oosponol. J Antibiot (Tokyo). 1972 Apr;25(4):239-42. [2]. Sonnenbichler J,et al. Influence of the Gloeophyllum metabolite oosponol and some synthetic analogues on protein and RNA synthesis in target cells. Eur J Biochem. 1997 May 15;246(1):45-9.