80629-35-2

80629-35-2 structure

Name: Captopril EP Impurity B
Chemical Name: 1-(3-bromo-2S-methylpropionyl)-pyrrolidine-2S-carboxylic acid
CAS Number: 80629-35-2
Molecular Formula: C₉H₁₄BrNO₃
Molecular Weight: 264.11600
Catalog: analytical chemistry Standard Pharmacopoeia Standards and Magazine Standards
Create Date: 2019-01-01 13:22:49
Modify Date: 2024-01-02 11:26:20
Captopril EP Impurity B is an impurity of Captopril. Captopril (SQ-14534), antihypertensive agent, is a thiol-containing competitive, orally active angiotensin-converting enzyme (ACE) inhibitor (IC50=0.025 μM)[1][2][3].

Name	1-(3-bromo-2S-methylpropionyl)-pyrrolidine-2S-carboxylic acid
Synonyms	1-[(2S)-3-Bromo-2-methyl-1-oxopropyl]-L-proline Captopril EP Impurity B Captopril Impurity 2

Description	Captopril EP Impurity B is an impurity of Captopril. Captopril (SQ-14534), antihypertensive agent, is a thiol-containing competitive, orally active angiotensin-converting enzyme (ACE) inhibitor (IC50=0.025 μM)[1][2][3].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
References	[1]. ANCA GABRIELA CÂRJE, et al. HPLC-UV METHOD APPROACH FOR THE ANALYSIS AND IMPURITY PROFILING OF CAPTOPRIL. [2]. Afrin S, et al. Eritadenine from Edible Mushrooms Inhibits Activity of Angiotensin Converting Enzyme in Vitro. J Agric Food Chem. 2016;64(11):2263-2268. [3]. Esmaeili S, et al. Captopril/enalapril inhibit promiscuous esterase activity of carbonic anhydrase at micromolar concentrations: An in vitro study. Chem Biol Interact. 2017;265:24-35.

Precursor 0
DownStream 1
62571-86-2