622855-37-2

622855-37-2 structure

Name: Wee1 Inhibitor I
Chemical Name: 4-(2-chlorophenyl)-9-hydroxy-6H-pyrrolo[3,4-c]carbazole-1,3-dione
CAS Number: 622855-37-2
Molecular Formula: C₂₀H₁₁ClN₂O₃
Molecular Weight: 362.76600
Catalog: Signaling Pathways Cell Cycle/DNA Damage Wee1
Create Date: 2017-03-16 03:06:14
Modify Date: 2026-08-06 08:45:09
WEE1-IN-4 is a potent checkpoint Wee1 kinase inhibitor with an IC50 of 0.011 μM[1].

Name	4-(2-chlorophenyl)-9-hydroxy-6H-pyrrolo[3,4-c]carbazole-1,3-dione
Synonyms	4-(2-chlorophenyl)-9-hydroxy-6H-pyrrolo[3,4-c]cbazole-1,3-dione WEE-1-IN-4,WEE1 IN 4,WEE1IN4 WEE1-IN-4 Wee1 Inhibitor Pyrrolo[3,4-c]cbazole-1,3(2H,6H)-dione, 4-(2-chlorophenyl)-9-hydroxy Kinome_3672 HMS3229P19

Description	WEE1-IN-4 is a potent checkpoint Wee1 kinase inhibitor with an IC50 of 0.011 μM[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Wee1
Target	IC50: 0.011 μM (Wee1 kinase) pIC50: 7.96[1]
References	[1]. Kanin Wichapong, et al. Receptor-based 3D-QSAR studies of checkpoint Wee1 kinase inhibitors. Eur J Med Chem. 2009 Apr;44(4):1383-95.