Wee1 Inhibitor I

Modify Date: 2024-01-19 20:34:15

Wee1 Inhibitor I Structure
Wee1 Inhibitor I structure
Common Name Wee1 Inhibitor I
CAS Number 622855-37-2 Molecular Weight 362.76600
Density N/A Boiling Point N/A
Molecular Formula C20H11ClN2O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Wee1 Inhibitor I


WEE1-IN-4 is a potent checkpoint Wee1 kinase inhibitor with an IC50 of 0.011 μM[1].

 Names

Name 4-(2-chlorophenyl)-9-hydroxy-6H-pyrrolo[3,4-c]carbazole-1,3-dione
Synonym More Synonyms

 Wee1 Inhibitor I Biological Activity

Description WEE1-IN-4 is a potent checkpoint Wee1 kinase inhibitor with an IC50 of 0.011 μM[1].
Related Catalog
Target

IC50: 0.011 μM (Wee1 kinase) pIC50: 7.96[1]

References

[1]. Kanin Wichapong, et al. Receptor-based 3D-QSAR studies of checkpoint Wee1 kinase inhibitors. Eur J Med Chem. 2009 Apr;44(4):1383-95.

 Chemical & Physical Properties

Molecular Formula C20H11ClN2O3
Molecular Weight 362.76600
Exact Mass 362.04600
PSA 85.68000
LogP 4.24110

 Synonyms

Wee1 Inhibitor
Kinome_3672
HMS3229P19