84777-85-5

84777-85-5 structure

Name: Virustomycin A
Chemical Name: (5R)-2,4-Dideoxy-1-C-{(2S,3R,4S)-4-[(3S,4Z,6Z,9R,10S,11S,12R,13R,14Z,16E)-11-ethyl-10,12-dihydroxy-3,17-dimethoxy-7,9,13,15-tetramethyl-18-oxooxacyclooctadeca-4,6,14,16-tetraen-2-yl]-3-hydroxy-2-pentanyl}-3-O-{(2E)-4-[(2-hydroxy-5-oxo-1-cyclopenten-1-yl)amino]-4-oxo-2-butenoyl}-4-methyl-5-[(1Z)-1-propen-1-yl]-α-D-threo-pentopyranose
CAS Number: 84777-85-5
Molecular Formula: C₄₈H₇₁NO₁₄
Molecular Weight: 886.08
Catalog: Research Areas Infection
Create Date: 2017-11-20 21:54:04
Modify Date: 2024-01-12 12:50:23
Virustomycin A is a nature product that could be isolated from Streptomyces. Virustomycin A has selective and potent antitrypanosomal activity[1][2].

Name	(5R)-2,4-Dideoxy-1-C-{(2S,3R,4S)-4-[(3S,4Z,6Z,9R,10S,11S,12R,13R,14Z,16E)-11-ethyl-10,12-dihydroxy-3,17-dimethoxy-7,9,13,15-tetramethyl-18-oxooxacyclooctadeca-4,6,14,16-tetraen-2-yl]-3-hydroxy-2-pentanyl}-3-O-{(2E)-4-[(2-hydroxy-5-oxo-1-cyclopenten-1-yl)amino]-4-oxo-2-butenoyl}-4-methyl-5-[(1Z)-1-propen-1-yl]-α-D-threo-pentopyranose
Synonyms	α-D-threo-Pentopyranose, 2,4-dideoxy-1-C-[(1S,2R,3S)-3-[(3S,4Z,6Z,9R,10S,11S,12R,13R,14Z,16E)-11-ethyl-10,12-dihydroxy-3,17-dimethoxy-7,9,13,15-tetramethyl-18-oxooxacyclooctadeca-4,6,14,16-tetraen -2-yl]-2-hydroxy-1-methylbutyl]-3-O-[(2E)-4-[(2-hydroxy-5-oxo-1-cyclopenten-1-yl)amino]-1,4-dioxo-2-buten-1-yl]-4-methyl-5-C-[(1Z)-1-propen-1-yl]-, (5R)- (2E)-4-((2-(4-((4Z,6Z,14Z,16E)-11-ethyl-10,12-dihydroxy-3,17-dimethoxy-7,9,13,15-tetramethyl-18-oxooxacyclooctadeca-4,6,14,16-tetraen-2-yl)-3-hydroxypentan-2-yl)-2-hydroxy-5-methyl-6-((Z)-prop-1-en-1-yl)tetrahydro-2H-pyran-4-yl)oxy)-N-(2-hydroxy-5-oxocyclopent-1-en-1-yl)-4-oxobut-2-enimidic acid (5R)-2,4-Dideoxy-1-C-{(2S,3R,4S)-4-[(3S,4Z,6Z,9R,10S,11S,12R,13R,14Z,16E)-11-ethyl-10,12-dihydroxy-3,17-dimethoxy-7,9,13,15-tetramethyl-18-oxooxacyclooctadeca-4,6,14,16-tetraen-2-yl]-3-hydroxy-2-penta ;nyl}-3-O-{(2E)-4-[(2-hydroxy-5-oxo-1-cyclopenten-1-yl)amino]-4-oxo-2-butenoyl}-4-methyl-5-[(1Z)-1-propen-1-yl]-α-D-threo-pentopyranose

Description	Virustomycin A is a nature product that could be isolated from Streptomyces. Virustomycin A has selective and potent antitrypanosomal activity[1][2].
Related Catalog	Research Areas >> Infection
References	[1]. Otoguro K, et, al. Selective and potent in vitro antitrypanosomal activities of ten microbial metabolites. J Antibiot (Tokyo). 2008 Jun;61(6):372-8. [2]. Nara A, et, al. Characterization of bafilomycin biosynthesis in Kitasatospora setae KM-6054 and comparative analysis of gene clusters in Actinomycetales microorganisms. J Antibiot (Tokyo). 2017 May;70(5):616-624.