113190-92-4

113190-92-4 structure

Name: PPPA
Chemical Name: (2R,4S)-4-(3-phosphonopropyl)piperidine-2-carboxylic acid
CAS Number: 113190-92-4
Molecular Formula: C₉H₁₈NO₅P
Molecular Weight: 251.21700
Catalog: Signaling Pathways Membrane Transporter/Ion Channel iGluR
Create Date: 2016-07-03 08:33:59
Modify Date: 2024-01-06 17:26:15
PPPA is a competitive NMDA receptor antagonist that displays moderate selectivity for NR2A-containing receptors[1][2].

Name	(2R,4S)-4-(3-phosphonopropyl)piperidine-2-carboxylic acid
Synonyms	Neuromedin S (rat) cis-4-(3-phosphonoprop-1-yl)piperidine-2-carboxylic acid (2R,4S)-4-(3-PHOSPHONOPROPYL)-2-PIPERIDINECARBOXYLIC ACID 2-Piperidinecarboxylic acid,4-(3-phosphonopropyl)-,cis

Description	PPPA is a competitive NMDA receptor antagonist that displays moderate selectivity for NR2A-containing receptors[1][2].
Related Catalog	Signaling Pathways >> Neuronal Signaling >> iGluR Research Areas >> Neurological Disease Signaling Pathways >> Membrane Transporter/Ion Channel >> iGluR
References	[1]. Benveniste M, Mayer ML. Effect of extracellular pH on the potency of N-methyl-D-aspartic acid receptor competitive antagonists. Mol Pharmacol. 1992 Oct;42(4):679-86. [2]. Feng B, et al. The effect of competitive antagonist chain length on NMDA receptor subunit selectivity. Neuropharmacology. 2005 Mar;48(3):354-9.