150351-30-7

150351-30-7 structure

Name: PD 134922
Chemical Name: (2S,4S,5S)-N-butyl-6-cyclohexyl-4-hydroxy-5-[[(2S)-2-[[(2S)-2-(morpholin-4-ylsulfonylamino)-3-phenylpropanoyl]amino]pent-4-enoyl]amino]-2-propan-2-ylhexanamide
CAS Number: 150351-30-7
Molecular Formula: C₃₇H₆₁N₅O₇S
Molecular Weight: 719.97500
Catalog: Signaling Pathways Metabolic Enzyme/Protease HIV Protease
Create Date: 2017-09-13 05:25:23
Modify Date: 2024-03-26 16:14:03
PD 134922 is a potent renin and HIV-1 protease inhibitor with an IC50 of 15 nM against HIV-1 protease[1].

Name	(2S,4S,5S)-N-butyl-6-cyclohexyl-4-hydroxy-5-[[(2S)-2-[[(2S)-2-(morpholin-4-ylsulfonylamino)-3-phenylpropanoyl]amino]pent-4-enoyl]amino]-2-propan-2-ylhexanamide

Description	PD 134922 is a potent renin and HIV-1 protease inhibitor with an IC50 of 15 nM against HIV-1 protease[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Metabolic Enzyme/Protease >> HIV Protease Signaling Pathways >> Metabolic Enzyme/Protease >> Renin
Target	IC50: 15 nM (HIV-1 protease)[1]
References	[1]. Humblet CC, et al. Characterization of two structurally novel HIV-1 protease inhibitors identified by rational selection. Antiviral Res. 1993 May;21(1):73-84.