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185304-42-1

185304-42-1 structure
185304-42-1 structure
  • Name: RPR132595A
  • Chemical Name: 7-Ethyl-10-(4-amino-1-piperidino)carbonyloxycamptothecin
  • CAS Number: 185304-42-1
  • Molecular Formula: C28H30N4O6
  • Molecular Weight: 518.56100
  • Catalog: Research Areas Others
  • Create Date: 2016-10-23 03:21:32
  • Modify Date: 2024-01-10 12:36:41
  • RPR132595A (NPC) is an active metabolite of CPT-11, which is generated by cytochrome P-450 3A4 (CYP3A4) and finally excreted through urine[1].

Name 7-Ethyl-10-(4-amino-1-piperidino)carbonyloxycamptothecin
Description RPR132595A (NPC) is an active metabolite of CPT-11, which is generated by cytochrome P-450 3A4 (CYP3A4) and finally excreted through urine[1].
Related Catalog
References

[1]. Alvau MD, et al. Enzyme-Based Electrochemical Biosensor for Therapeutic Drug Monitoring of Anticancer Drug Irinotecan.Anal Chem. 2018 May 15;90(10):6012-6019.

Density 1.471g/cm3
Boiling Point 861.388ºC at 760 mmHg
Melting Point 178-184ºC
Molecular Formula C28H30N4O6
Molecular Weight 518.56100
Flash Point 474.75ºC
Exact Mass 518.21700
PSA 136.98000
LogP 3.20210
Vapour Pressure 0mmHg at 25°C
Index of Refraction 1.71