RPR132595A

Modify Date: 2024-01-10 12:36:41

RPR132595A Structure
RPR132595A structure
Common Name RPR132595A
CAS Number 185304-42-1 Molecular Weight 518.56100
Density 1.471g/cm3 Boiling Point 861.388ºC at 760 mmHg
Molecular Formula C28H30N4O6 Melting Point 178-184ºC
MSDS N/A Flash Point 474.75ºC

 Use of RPR132595A


RPR132595A (NPC) is an active metabolite of CPT-11, which is generated by cytochrome P-450 3A4 (CYP3A4) and finally excreted through urine[1].

 Names

Name 7-Ethyl-10-(4-amino-1-piperidino)carbonyloxycamptothecin

 RPR132595A Biological Activity

Description RPR132595A (NPC) is an active metabolite of CPT-11, which is generated by cytochrome P-450 3A4 (CYP3A4) and finally excreted through urine[1].
Related Catalog
References

[1]. Alvau MD, et al. Enzyme-Based Electrochemical Biosensor for Therapeutic Drug Monitoring of Anticancer Drug Irinotecan.Anal Chem. 2018 May 15;90(10):6012-6019.

 Chemical & Physical Properties

Density 1.471g/cm3
Boiling Point 861.388ºC at 760 mmHg
Melting Point 178-184ºC
Molecular Formula C28H30N4O6
Molecular Weight 518.56100
Flash Point 474.75ºC
Exact Mass 518.21700
PSA 136.98000
LogP 3.20210
Vapour Pressure 0mmHg at 25°C
Index of Refraction 1.71
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