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2312-35-8

2312-35-8 structure
2312-35-8 structure

Name propargite
Synonyms Propargite
d014
do14
Propargiet
Sulfurous acid, 2-[4-(1,1-dimethylethyl)phenoxy]cyclohexyl 2-propynyl ester
(1RS,2RS
comite
Sulfurous Acid 2-[4-(1,1-Dimethylethyl)phenoxy]cyclohexyl 2-Propynyl Ester
EINECS 219-006-1
2-[4-(2-Methyl-2-propanyl)phenoxy]cyclohexyl 2-propyn-1-yl sulfite
Omit
BPPS
MFCD00072448
Omite
progi
1RS,2SR)-2-(4-tert-butylphenoxy)cyclohexyl prop-2-ynyl sulfite
2-(4-tert-Butylphenoxy)cyclohexyl 2-propynyl sulfite
2-(4-tert-Butylphenoxy)cyclohexyl prop-2-yn-1-yl sulfite
PROP 57
omait
2-(4-tert-Butylphenoxy)cyclohexyl-prop-2-in-1-ylsulfit
Sulfurous Acid 2-(p-tert-Butylphenoxy)cyclohexyl 2-Propynyl Ester
(1Ξ,2Ξ)-2-(4-tert-butylphenoxy)cyclohexyl prop-2-yn-1-yl sulfite
Propargil
2-[4-(1,1-dimethylethyl)phenoxy]cyclohexyl 2-propyn-1-yl sulfite
Sulfurous acid, 2-[4-(1,1-dimethylethyl)phenoxy]cyclohexyl 2-propyn-1-yl ester
2-(4-(tert-Butyl)phenoxy)cyclohexyl prop-2-yn-1-yl sulfite
RETADOR
Description Propargite is a pesticide used to kill mites. Propargite induces β-cell necrosis preceded by DNA damage. Propargite induces MIN6 cell death with an IC50 of 1 μM[1].
Related Catalog
References

[1]. Ting Zhou, et al. A hPSC-based Platform to Discover Gene-Environment Interactions That Impact Human β-cell and Dopamine Neuron Survival. Nat Commun. 2018 Nov 16;9(1):4815.

Density 1.2±0.1 g/cm3
Boiling Point 450.7±45.0 °C at 760 mmHg
Molecular Formula C19H26O4S
Molecular Weight 350.472
Flash Point 226.4±28.7 °C
Exact Mass 350.155182
PSA 63.97000
LogP 4.81
Vapour Pressure 0.0±1.1 mmHg at 25°C
Index of Refraction 1.561

CHEMICAL IDENTIFICATION

RTECS NUMBER :
WT2900000
CHEMICAL NAME :
Sulfurous acid, 2-(p-tert-butylphenoxy)cyclohexyl-2-propynyl ester
CAS REGISTRY NUMBER :
2312-35-8
LAST UPDATED :
199701
DATA ITEMS CITED :
7
MOLECULAR FORMULA :
C19-H26-O4-S
MOLECULAR WEIGHT :
350.51
WISWESSER LINE NOTATION :
L6TJ AOSO&O2UU1 BOR DX1&1&1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1480 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 14,515,1969
TYPE OF TEST :
LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>940 mg/m3/4H
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,719,1991
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
250 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
WRPCA2 World Review of Pest Control. (London, UK) V.1-10, 1962-71. Discontinued. Volume(issue)/page/year: 9,119,1970
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Unreported
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
780 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
TGANAK Tsitologiya i Genetika. Cytology and Genetics. For English translation, see CYGEDX. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1967- Volume(issue)/page/year: 16(1),45,1982
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
10300 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
85JFAN "Agrochemicals Handbook," with updates, Hartley, D., and H. Kidd, eds., Nottingham, Royal Soc. of Chemistry, 1983-86 Volume(issue)/page/year: A589,1985 *** U.S. STANDARDS AND REGULATIONS *** EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year: 54,7740,1989
Symbol GHS05 GHS06 GHS08 GHS09
GHS05, GHS06, GHS08, GHS09
Signal Word Danger
Hazard Statements H315-H318-H331-H351-H410
Precautionary Statements P261-P273-P280-P305 + P351 + P338-P311-P501
Personal Protective Equipment Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes T:Toxic
Risk Phrases R23;R38;R40;R41;R50/53
Safety Phrases S26-S36/37/39-S45-S60-S61
RIDADR UN 2810
RTECS WT2900000
Packaging Group III
Hazard Class 9
HS Code 2920909014
HS Code 2920909014
Summary 2920909014 2-(4-(tert-butyl)phenoxy)cyclohexyl prop-2-yn-1-yl sulfite。supervision conditions:s(import or export registration certificate for pesticides)。VAT:17.0%。tax rebate rate:9.0%。MFN tarrif:6.5%。general tariff:30.0%