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68157-60-8 1398065-87-6

68157-60-8

68157-60-8 structure
68157-60-8 structure
  • Name: forchlorfenuron
  • Chemical Name: forchlorfenuron
  • CAS Number: 68157-60-8
  • Molecular Formula: C12H10ClN3O
  • Molecular Weight: 247.680
  • Catalog: Chemical pesticide Plant Growth Regulator
  • Create Date: 2018-06-05 08:00:00
  • Modify Date: 2024-01-02 00:09:37
  • Forchlorfenuron is plant growth regulator and cytokinin; can be used to increase fruit size of fruits, such as kiwi fruit and grapes.
Name forchlorfenuron
Synonyms N-(2-chloropyridin-4-yl)-N’-phenylurea
KT-30
N-(2-chloro-4-pyridinyl)-N’-phenylurea
4pu30
CN-11-3183
CPPU
fulmet
1-(2-Chloro-4-Pyridyl)-3-Phenylurea
MFCD00059898
SITOFEX
v3183
cn11-3138
4-CPPU
Description Forchlorfenuron is plant growth regulator and cytokinin; can be used to increase fruit size of fruits, such as kiwi fruit and grapes.
Related Catalog
In Vitro Forchlorfenuron is a plant growth regulator, applied extensively to increase kiwifruit size and weight. Cytotoxicity of forchlorfenuron and its metabolites are tested through Sulforhodamine B assays against CHO cells. Forchlorfenuron exhibits significant cytotoxicity against CHO cells with an IC50 of 12.12±2.14 μM[1]. The half-lives offorchlorfenuron were 15.8-23.0 days, the final residues of forchlorfenuron in pulp were all ≤0.002 mg/kg, and most of the residues were concentrated in the peel. The risk assessment revealed that no significant potential health risk would be induced by forchlorfenuron in citrus fruits. Therefore, it could be safe to apply forchlorfenuron in citrus fruits[2].
Cell Assay CHO cells are cultured in high-glucose DMEM medium. Forchlorfenuron and its kiwifruit metabolites are dissolved in DMSO and diluted in culture media. Cells are seeded in a 96-well flat microtiter plate for 24 h and are then incubated for an additional 48 h with various concentrations of the compounds. Next, cells are fixed with 10% trichloroacetic acid and incubated for 60 min at 4 °C. The supernatant is discarded, then the plates are washed. Using 0.4% SRB solution dissolved in 1% acetic acid, the cell layer is strained, then the plates are incubated for 20 min at room temperature. The stained cells is solubilized in 10 mM un-buffered Tris base and optical density (OD) is measured at 560 nm[1].
References

[1]. Zhang Z, et al. Identification, synthesis, and safety assessment of forchlorfenuron (1-(2-chloro-4-pyridyl)-3-phenylurea) and its metabolites in kiwifruits. J Agric Food Chem. 2015 Mar 25;63(11):3059-66.

[2]. Chen W, et al. Dissipation and residue of forchlorfenuron in citrus fruits. Bull Environ Contam Toxicol. 2013 Jun;90(6):756-60.
Density 1.3±0.1 g/cm3
Boiling Point 426.5±55.0 °C at 760 mmHg
Melting Point 170-172°C
Molecular Formula C12H10ClN3O
Molecular Weight 247.680
Flash Point 211.7±31.5 °C
Exact Mass 247.051239
PSA 54.02000
LogP 3.83
Vapour Pressure 0.0±1.1 mmHg at 25°C
Index of Refraction 1.629
Storage condition 2-8°C
Symbol GHS08 GHS09
GHS08, GHS09
Signal Word Warning
Hazard Statements H351-H411
Precautionary Statements P273-P281
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi: Irritant;
Risk Phrases R36/37
Safety Phrases S26-S36
RIDADR UN3077 9/PG 3
WGK Germany 3
RTECS YS7182500
HS Code 2933399090
HS Code 2933399090
Summary 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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title: CAS No. 68157-60-8 | Chemsrc address: https://m.chemsrc.com/en/baike/1154234.html

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