4239-24-1
4239-24-1 structure
- Name: 1,6-Bis(mesyloxy)hexane
- Chemical Name: 6-methylsulfonyloxyhexyl methanesulfonate
- CAS Number: 4239-24-1
- Molecular Formula: C8H18O6S2
- Molecular Weight: 274.35500
- Catalog: Signaling Pathways Antibody-drug Conjugate ADC Linker
- Create Date: 2016-06-06 00:08:24
- Modify Date: 2024-01-05 08:36:37
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16-Bismesyloxyhexane is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
| Name | 6-methylsulfonyloxyhexyl methanesulfonate |
|---|---|
| Synonyms |
1,6-hexanediyl dimethanesulfonate
Hexane dimethanesulphonate hexamethylene dimesylate CTK8I7029 1,6-Bis(mesyloxy)hexane hexane-1,6-diyl bis[methanesulfonate] 1,6-bis-methanesulfonyloxy-hexane 1,6-hexyl dimesylate 1,6-Hexanediol,dimethanesulfonate AC1L3RSR Hexasulphan 1,6-Bis-methansulfonyloxy-hexan Hexasulfan |
| Description | 16-Bismesyloxyhexane is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. |
|---|---|
| Related Catalog | |
| Target |
Cleavable |
| In Vitro | ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1]. |
| References |
| Density | 1.273g/cm3 |
|---|---|
| Boiling Point | 474.6ºC at 760 mmHg |
| Molecular Formula | C8H18O6S2 |
| Molecular Weight | 274.35500 |
| Flash Point | 240.8ºC |
| Exact Mass | 274.05400 |
| PSA | 103.50000 |
| LogP | 2.66080 |
| Index of Refraction | 1.471 |
|
~92%
4239-24-1 |
| Literature: Li, Yi; Hesse, Manfred Helvetica Chimica Acta, 2003 , vol. 86, # 2 p. 310 - 323 |
| Precursor 2 | |
|---|---|
| DownStream 1 | |
