52869-18-8

52869-18-8 structure

Name: SSAA09E3
Chemical Name: N-(9,10-dioxoanthracen-2-yl)benzamide
CAS Number: 52869-18-8
Molecular Formula: C₂₁H₁₃NO₃
Molecular Weight: 327.33300
Catalog: Signaling Pathways Anti-infection SARS-CoV
Create Date: 2017-09-19 02:45:12
Modify Date: 2024-11-14 01:48:08
SSAA09E3 is a SARS-CoV entry inhibitor that inhibits SARS/HIV pseudotyped virus entry with an EC50 of 9.7 μM in 293T cells and inhibits SARS-CoV infection of Vero cells with an EC50 of 0.15 μM[1][2].

Name	N-(9,10-dioxoanthracen-2-yl)benzamide
Synonyms	2-Benzoylamino-anthrachinon N-(9,10-dioxo-9,10-dihydroanthracen-2-yl)benzamide 2-Benzamino-anthrachinon N-(9,10-Dioxo-9,10-dihydro-[2]anthryl)-benzamid N-(9,10-dioxo-9,10-dihydro-[2]anthryl)-benzamide 2-benzamidoanthraquinone Anthraquinone,2-benzamido

Description	SSAA09E3 is a SARS-CoV entry inhibitor that inhibits SARS/HIV pseudotyped virus entry with an EC50 of 9.7 μM in 293T cells and inhibits SARS-CoV infection of Vero cells with an EC50 of 0.15 μM[1][2].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> SARS-CoV
Target	SARS-CoV[1]
In Vitro	SSAA09E3 blocks viral entry by inhibiting fusion of the viral membrane with the host cell membrane[1]. SSAA09E3 inhibits later stages of viral entry[2].

Molecular Formula	C₂₁H₁₃NO₃
Molecular Weight	327.33300
Exact Mass	327.09000
PSA	66.73000
LogP	4.09830

591-50-4

201230-82-2

117-79-3

~83%

52869-18-8

Literature: Quesnel, Jeffrey S.; Arndtsen, Bruce A. Journal of the American Chemical Society, 2013 , vol. 135, # 45 p. 16841 - 16844

98-88-4

117-79-3

52869-18-8

Literature: Yakovlev, Yu. Yu.; Nurmukhametov, R. N.; Barashkov, N. N.; Klimenko, V. G. Russian Journal of Physical Chemistry, 1991 , vol. 65, # 1 p. 110 - 111 Zhurnal Fizicheskoi Khimii, 1991 , vol. 65, p. 216 - 219