- Shanghai Nianxing Industrial Co., Ltd
- China
- Product Name: 2-Iminobiotin
- Price:
- Purity: 98.0%
- Stocking Period: 10 Day
- Contact: Yang
- Shanghai Jizhi Biochemical Technology Co., Ltd
- China
- Product Name: 2-Iminobiotin
- Price: ￥3358.0/100mg ￥658.0/25mg
- Purity: 98.0%
- Stocking Period: Inquiry
- Contact: Liu jia
- Dayang Chem (Hangzhou) Co., Ltd.
- China
- Product Name: 2-Iminobiotin
- Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
- Purity: 98.0%
- Stocking Period: Inquiry
- Contact: Ms Wang
13395-35-2
13395-35-2 structure
- Name: 2-Iminobiotin
- Chemical Name: 5-[(3aS,4S,6aR)-2-amino-3a,4,6,6a-tetrahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoic acid
- CAS Number: 13395-35-2
- Molecular Formula: C10H17N3O2S
- Molecular Weight: 243.326
- Catalog: Signaling Pathways Immunology/Inflammation NO Synthase
- Create Date: 2018-02-22 08:00:00
- Modify Date: 2024-01-02 13:20:29
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2-Iminobiotin (Guanidinobiotin) is a biotin (vitamin H or B7) analog. 2-Iminobiotin is a reversible nitric oxide synthases inhibitor with Kis of 21.8 and 37.5μM for murine iNOS and rat n-cNOS, respectively[1]. 2-Iminobiotin superimposes on hypothermia protects human neuronal cells from hypoxia-induced cell damage[2].
| Name | 5-[(3aS,4S,6aR)-2-amino-3a,4,6,6a-tetrahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoic acid |
|---|---|
| Synonyms |
2izl
Guanidinobiotin Hexahydro-2-imino-1H-thieno[3,4-d]imidazole-4-pentanoic acid 1H-Thieno[3,4-d]imidazole-4-pentanoic acid, 2-amino-3a,4,6,6a-tetrahydro-, (3aS,4S,6aR)- MFCD00149243 2-Iminobiotin EINECS 236-308-9 Guanidinobiotin 5-[(3aR,6S,6aS)-2-Amino-3a,4,6,6a-tetrahydro-1H-thieno[3,4-d]imidazol-6-yl]pentanoic acid |
| Description | 2-Iminobiotin (Guanidinobiotin) is a biotin (vitamin H or B7) analog. 2-Iminobiotin is a reversible nitric oxide synthases inhibitor with Kis of 21.8 and 37.5μM for murine iNOS and rat n-cNOS, respectively[1]. 2-Iminobiotin superimposes on hypothermia protects human neuronal cells from hypoxia-induced cell damage[2]. |
|---|---|
| Related Catalog | |
| Target |
Nitric oxide synthases[1] |
| References |
| Density | 1.6±0.1 g/cm3 |
|---|---|
| Boiling Point | 477.3±55.0 °C at 760 mmHg |
| Molecular Formula | C10H17N3O2S |
| Molecular Weight | 243.326 |
| Flash Point | 242.5±31.5 °C |
| Exact Mass | 243.104141 |
| PSA | 110.51000 |
| LogP | -0.36 |
| Vapour Pressure | 0.0±2.6 mmHg at 25°C |
| Index of Refraction | 1.737 |
| Storage condition | 2~8°C |
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| Hazard Codes | Xi |
| Safety Phrases | 22-24/25 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
|
~%
13395-35-2 |
| Literature: Journal of Biological Chemistry, , vol. 187, p. 29,31 |
