61839-19-8

61839-19-8 structure

Name: phosphocyclocreatine
Chemical Name: 2-(2-imino-3-phosphonoimidazolidin-1-yl)acetic acid
CAS Number: 61839-19-8
Molecular Formula: C₅H₁₀N₃O₅P
Molecular Weight: 223.12400
Catalog: Research Areas Cancer
Create Date: 2017-12-01 03:45:34
Modify Date: 2024-01-22 19:16:42
Cyclocreatine phosphate is an anti-tumor agent. Cyclocreatine phosphate is the proposed active form of cyclocreatine (CCr), a substrate analogue of creatine kinase. Cyclocreatine phosphate has anti-tumour activity and can be used for the research of cancer[1].

Name	2-(2-imino-3-phosphonoimidazolidin-1-yl)acetic acid
Synonyms	Phosphocyclocreatine N-Phosphorylcyclocreatine [(2e)-2-imino-3-phosphonoimidazolidin-1-yl]acetic acid Cyclocreatine phosphate

Description	Cyclocreatine phosphate is an anti-tumor agent. Cyclocreatine phosphate is the proposed active form of cyclocreatine (CCr), a substrate analogue of creatine kinase. Cyclocreatine phosphate has anti-tumour activity and can be used for the research of cancer[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
In Vivo	Cyclocreatine phosphate (CCr'P) (i.p.; 37.5 mg/mL; 0.2 mL, twice daily) has anti-tumor activity without any notable signs of toxicity in a mouse xenograft model for human prostate cancer[1]. Animal Model: Athymic (CDl-Nu/Nu) male mice[1] Dosage: 37.5 mg/mL Administration: intraperitoneally , 0.2 mL, twice daily Result: Showed anti-tumor effect.
References	[1]. Rima Kaddurah-Daouk, et al. Creatine phosphate, creatine phosphate analogs, and uses therefor. Patent. WO1994016712A1.