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6691-83-4

6691-83-4 structure
6691-83-4 structure
  • Name: Cinobufaginol
  • Chemical Name: Cinobufaginol
  • CAS Number: 6691-83-4
  • Molecular Formula: C26H34O7
  • Molecular Weight: 458.54400
  • Catalog: Research Areas Cancer
  • Create Date: 2016-10-12 04:49:09
  • Modify Date: 2024-01-06 00:57:04
  • Cinobufaginol is a natural bufadienolide isolated from toad venom which has been widely used for centuries in China to treat different diseases, especially for cancer. Cinobufaginol potently inhibits the activity against human nasopharyngeal carcinoma cell lines with IC50s of 803 μΜ and 1.270 μΜ for CNE-1 and CNE-2Z, respectively[1].

Name Cinobufaginol
Synonyms 5beta-Bufa-20,22-dienolide,14,15beta-epoxy-3beta,16beta,19-trihydroxy-,16-acetate
Description Cinobufaginol is a natural bufadienolide isolated from toad venom which has been widely used for centuries in China to treat different diseases, especially for cancer. Cinobufaginol potently inhibits the activity against human nasopharyngeal carcinoma cell lines with IC50s of 803 μΜ and 1.270 μΜ for CNE-1 and CNE-2Z, respectively[1].
Related Catalog
References

[1]. Liu JS, et al. Anti-tumor effects and 3D-quantitative structure-activity relationship analysis of bufadienolidesfrom toad venom. Fitoterapia. 2019 Apr;134:362-371.

Molecular Formula C26H34O7
Molecular Weight 458.54400
Exact Mass 458.23000
PSA 109.50000
LogP 2.77230
Hazard Codes Xi