120020-26-0
120020-26-0 structure
- Name: Artelinic acid
- Chemical Name: Artelinic acid
- CAS Number: 120020-26-0
- Molecular Formula: C23H30O7
- Molecular Weight: 418.48000
- Catalog: Research Areas Infection
- Create Date: 2016-04-26 19:57:01
- Modify Date: 2024-01-03 05:15:23
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Artelinic acid, a derivative of Artemisinin, is an antimalarial drug for the treatment of multidrug resistant strains of Plasmodium falciparum. Artelinic acid can be administered by various routes of administration, including intravenous, intramuscular and oral routes[1][2].
| Name | Artelinic acid |
|---|
| Description | Artelinic acid, a derivative of Artemisinin, is an antimalarial drug for the treatment of multidrug resistant strains of Plasmodium falciparum. Artelinic acid can be administered by various routes of administration, including intravenous, intramuscular and oral routes[1][2]. |
|---|---|
| Related Catalog | |
| In Vivo | Artelinic acid (10 mg/kg; i.v.) has an elimination time t1/2 of 0.37 hours, a CL of 14.99 mL/min/kg, a Vss of 9.52 L and a AUC0-12h of 11219 ng h/mL for dogs[1]. Artelinic acid (10 mg/kg; intramuscular) has an elimination time t1/2 of 6.14 hours, a CL of 14.58 mL/min/kg, a Vss of 36.1 L and a AUC0-12h of 96372 ng h/mL for dogs[1]. Artelinic acid (10 mg/kg; oral) has an elimination time t1/2 of 2.21 hours, a CL of 14.6 mL/min/kg, a Vss of 16.2 L and a AUC0-12h of 8839 ng h/mL for dogs[1]. Animal Model: Adult male beagle dogs 3-5 years old[1] Dosage: 10 mg/kg Administration: i.v. (Pharmacokinetic Analysis) Result: Had an elimination time t1/2 of 0.37 hours, a CL of 14.99 mL/min/kg, a Vss of 9.52 L and a AUC0-12h of 11219 ng h/mL for dogs. |
| References |
| Molecular Formula | C23H30O7 |
|---|---|
| Molecular Weight | 418.48000 |
| Exact Mass | 418.19900 |
| PSA | 83.45000 |
| LogP | 4.10940 |
| Vapour Pressure | 2.28E-12mmHg at 25°C |