869499-38-7

869499-38-7 structure

Name: GSK345931A
Chemical Name: sodium,6-[2-[5-chloro-2-(2-methylpropoxy)phenyl]phenyl]pyridine-2-carboxylate
CAS Number: 869499-38-7
Molecular Formula: C₂₂H₁₉ClNNaO₃
Molecular Weight: 403.83
Catalog: Signaling Pathways GPCR/G Protein Prostaglandin Receptor
Create Date: 2017-05-23 07:42:00
Modify Date: 2025-08-22 15:52:36
GSK345931A is an EP1 receptor antagonist. GSK345931A shows measurable CNS penetration in the mouse and rat and potent analgesic efficacy in acute and sub-chronic models of inflammatory pain[1].

Name	sodium,6-[2-[5-chloro-2-(2-methylpropoxy)phenyl]phenyl]pyridine-2-carboxylate
Synonyms	unii-u73bv4mml7

Description	GSK345931A is an EP1 receptor antagonist. GSK345931A shows measurable CNS penetration in the mouse and rat and potent analgesic efficacy in acute and sub-chronic models of inflammatory pain[1].
Related Catalog	Signaling Pathways >> GPCR/G Protein >> Prostaglandin Receptor Research Areas >> Inflammation/Immunology Research Areas >> Neurological Disease
Target	EP1
References	[1]. Hall A, et al. Discovery of GSK345931A: An EP(1) receptor antagonist with efficacy in preclinical models of inflammatory pain. Bioorg Med Chem Lett. 2009 Jan 15;19(2):497-501.